Molecular Chaperones

Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview cha...

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Bibliographic Details
Other Authors: Ellis, R.J. (Editor), Laskey, R.A. (Editor), Lorimer, G.H. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1993, 1993
Edition:1st ed. 1993
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 8 Protein folding in the cell: functions of two families of molecular chaperone, hsp 60 and TF55-TCP1
  • Discussion: N. J. Cowan, P. Viitanen, P. Mickletheaite, M.-J. Gething, H. Saibil, R. Jaenicke, C. Georgopoulos, F.-U. Hard, K. Willison
  • 9 Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells
  • Discussion: M.-J. Gething, A. R. Clarke, P. Viitanen, P. Lund, I. G. Haas, C. Georgopoulos
  • 10 The role of molecular chaperones in protein transport into the endoplasmic reticulum
  • Discussion: S. Lindquist, W. J. Welch, P. Viitanen, G. H. Lorimer
  • 11 Recognition of ligands by SecB, a molecular chaperone involved in bacterial protein export
  • Discussion: J. Murphy, P. Lund, W. J. Welch, P. Viitanen, R. Jaenicke, F.-U. Hartl, T. E. Creighton, R. A. Laskey, G. H. Lorimer
  • 12 Roles of molecular chaperones inprotein targeting to mitochondria
  • Discussion: W. J. Welch, A. Baker, M.-J. Gething, R. Jaenicke
  • 13 Molecular chaperones and the immune response
  • Discussion: W. J. Welch, M.-J. Gething, P. Lund, A. R. Coates, I. G. Haas, P. Viitanen
  • 14 Tumour suppressor genes and molecular chaperones
  • Discussion: W. J. Welch, P. Viitanen, G. H. Lorimer, M. Zylicz, M. F. Perutz116
  • 1 The general concept of molecular chaperones
  • 2 The role of nucleoplasmin in chromatin assembly and disassembly
  • Discussion: S. Lindquist, A. Horwich, N. W. Green, M.-J. Gething, W. Neupert, R. J. Ellis
  • 3 The Escherichia coli chaperones involved in DNA replication
  • Discussion: R. Jaenicke, M.-J. Gething, R. J. Ellis
  • 4 The role of heat-shock proteins in thermotolerance
  • Discussion: P. Viitanen, R. Jaenicke, A. Horwich, F.-U. Hard, R. J. Ellis, W. J. Welch
  • 5 What does protein refolding in vitro tell us about protein folding in the cell?
  • Discussion: A. R. Clarke, F.-U. Hard, G. H. Lorimer, R. J. Ellis, P. Viitanen
  • 6 Chaperonins and protein folding: unity and disunity of mechanisms
  • Discussion: N. C. Price, R. Jaenicke, F.-U. Hard, R. B. Freedman, M. Yoshida, W. J. Welch, B. O’Hara
  • 7 A chaperonin from a thermophilic bacterium, Thermus thermophilus
  • Discussion: G. H. Lorimer, R. Jaenicke, P. Viitanen, H. Saibil