Mechanics of Elastic Biomolecules

A representative cross-section of elastic biomolecules is covered in this volume, which combines seventeen contributions from leading research groups. State-of-the-art molecular mechanics experiments are described dealing with the elasticity of DNA and nucleoprotein complexes, titin and titin-like p...

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Bibliographic Details
Other Authors: Linke, W.A. (Editor), Granzier, H.L. (Editor), Kellermayer, M. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 2003, 2003
Edition:1st ed. 2003
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • DNA, Chromatin and Chromosomes
  • Mechanics and imaging of single DNA molecules
  • Stretching and imaging single DNA molecules and chromatin
  • Optical tweezers stretching of chromatin
  • Micromechanical studies of mitotic chromosomes
  • Elastic Invertebrate Muscle Proteins
  • Varieties of elastic protein in invertebrate muscles
  • Single-molecule measurement of elasticity of Serine-, Glutamate- and Lysine-Rich repeats of invertebrate connectin reveals that its elasticity is caused entropically by random coil structure
  • The Elastic Vertebrate Muscle Protein Titin
  • Titin as a modular spring: emerging mechanisms for elasticity control by titin in cardiac physiology and pathophysiology
  • Species variations in cDNA sequence and exon splicing patterns in the extensible I-band region of cardiac titin: relation to passive tension
  • Cardiac titin: molecular basis of elasticity and cellular contribution to elastic and viscous stiffness components in myocardium
  • Stretching and visualizing titin molecules: combining structure, dynamics and mechanics
  • Unfolding of titin domains studied by molecular dynamics simulations
  • Cytoskeletal Proteins
  • Mechanical response of single filamin A (ABP-280) molecules and its role in the actin cytoskeleton
  • Mechanics of vimentin intermediate filaments
  • Extracellular Matrix Proteins
  • Mechanics of elastin: molecular mechanism of biological elasticity and its relationship to contraction
  • Molecular basis for the extensibility of elastin
  • Stretching fibronectin
  • Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix