Surfactant Systems Their chemistry, pharmacy and biology

It is now twelve years since Solubilization by Surface-Active Agents appeared. Since the publication of that monograph the subject has expanded rapidly as the unique potential of surfactants has become known to a wider circle of scientists. In a recent review Menger (Accounts of Chemical Research, 1...

Full description

Bibliographic Details
Main Author: Attwood, D.
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1983, 1983
Edition:1st ed. 1983
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 9.5 Rheological characteristics of suspensions
  • 9.6 Crystal changes in suspensions
  • 9.7 Bacterial and other cell suspensions
  • References
  • 10. Aspects of surfactant toxicity
  • 10.1 Introduction
  • 10.2 Metabolism of surfactants
  • 10.3 Interactions of surfactants with membranes and membrane components
  • 10.4 Toxicology of surfactants
  • 10.5 Surfactants and plant systems
  • References
  • 11. Reactivity in surfactant systems
  • 11.1 Introduction
  • 11.2 Chemistry at interfaces
  • 11.3 Micellar reactions
  • 11.4 Stability of drugs in surfactant systems
  • 11.5 Stability of surfactant systems
  • 11.6 Polymerization of surface-active molecules
  • 11.7 Some analytical consequences of surfactant presence
  • References
  • 4. Surface activity and colloidal properties of drugs and naturally occurring substances
  • 4.1 Colloidal properties of drugs
  • 4.2 Some biological consequences of drug surface activity
  • 4.3 Biological relevance of micelle formation by drug molecules
  • 4.4 Naturally occurring micelle formers: the bile salts, phospholipids and related systems
  • References
  • 5. Solubilization
  • 5.1 Introduction
  • 5.2 Experimental methods of studying solubilization
  • 5.3 Mobility of solubilizate molecules
  • 5.4 Factors influencing solubilization
  • 5.5 Effect of solubilizate on micellar properties
  • 5.6 Solubilization in non-aqueous solvents
  • References
  • 6. Pharmaceutical aspects of solubilization
  • 6.1 Introduction
  • 6.2 Solubilization of drugs
  • 6.3 Pharmaceutical aspects of solubilization in non-aqueous systems
  • 6.4 Solubilization with block co-polymeric surfactants
  • 6.5 Polymer-surfactant interactions
  • 6.6 Surfactant interactions with oppositely charged species
  • 6.7 Hydrotropy in pharmaceutical systems
  • References
  • 7. Biological implications of surfactant presence in formulation
  • 7.1 Introduction
  • 7.2 Effect of surfactants on dissolution of drugs
  • 7.3 Effect of surfactants on membrane permeability
  • 7.4 Effect of surfactants on drug absorption
  • 7.5 Miscellaneous formulations and the influence of surfactants
  • 7.6 Surfactants and antibacterial activity
  • 7.7 Utilization of solubilization in drug delivery systems
  • References
  • 8. Emulsions
  • 8.1 Introduction
  • 8.2 Aspects of emulsion stability
  • 8.3 Multiple emulsions
  • 8.4 Microemulsions
  • 8.5 Viscosity and rheological characteristics of emulsions
  • 8.6 Solute disposition in emulsion systems
  • 8.7 Biopharmaceutical aspects of emulsions
  • References
  • 9. Surfactants in suspension systems
  • 9.1 Introduction
  • 9.2 Settling of suspended particles
  • 9.3 Suspension stability
  • 9.4 Effect of surfactants on the adsorptive capacity of suspensions
  • 1. Surface activity
  • 1.1 Amphipathic molecules
  • 1.2 Surface activity in aqueous solution
  • 1.3 Adsorption at liquid surfaces
  • 1.4 Adsorption at solid surfaces
  • 1.5 The wettability of solid surfaces
  • 1.6 Modification of the surface properties of solids by adsorbed surfactants
  • References
  • 2. Phase behaviour of surfactants
  • 2.1 Introduction
  • 2.2 Liquid crystalline phases in binary surfactant systems
  • 2.3 Liquid crystalline phases in ternary surfactant systems
  • 2.4 Factors affecting phase behaviour
  • 2.5 Quaternary phase systems
  • References
  • 3. Micellization
  • 3.1 Introduction
  • 3.2 Micellar structure
  • 3.3 Micellar shape
  • 3.4 Polydispersity of micellar size
  • 3.5 Factors affecting the CMC and micellar size
  • 3.6 Thermodynamics of micelle formation
  • 3.7 Kinetics of micelle formation
  • 3.8 Non-micellar association
  • 3.9 Micelle formation in non-aqueous solvents
  • References