Recognition of M. leprae antigens

Those who have had the privilege to visit the Sistine Chapel may remember the fres­ co painting of Jesus curing the leper (Marcus 1, 40-45). It seems that leprosy was not only known 2000 years ago but was also recognized as an important problem. Unfortunately, little has changed since then. Although...

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Bibliographic Details
Main Authors: Ottenhoff, Tom, de Vries, René (Author)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1987, 1987
Edition:1st ed. 1987
Series:Developments in Hematology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1 Introduction
  • 2 MHC Class II Ir/Is Gene Controlled Antigen Specific T Cell Activation and Disease Susceptibility: Leprosy, A Human Model
  • 3 HLA Class-II-Restricted Mycobacterium Leprae-Reactive T-Cell Clones from Leprosy Patients Established With a Minimal Requirement for Autologous Mononuclear Cells
  • 4 Mycobacterium Leprae Specific Protein Antigens Defined by Cloned Human Helper T Cells
  • 5 Cloned Suppressor T Cells from a Lepromatous Leprosy Patient Suppress Mycobacterium Leprae Reactive Helper T Cells
  • 6 Molecular Localization and Polymorphism of HLA Class II Restriction Determinants Defined by Mycobacterium Leprae Reactive Helper T Cell Clones from Leprosy Patients
  • 7 HLA-DR3 Molecules are the Products of an HLA Class II Immune Regulator Gene for Mycobacterium Leprae Predisposing to Tuberculoid Leprosy
  • 8 Evidence for an HLA-DR4 Associated Immune Response Gene for Mycobacterium Tuberculosis: A Clue to the Pathogenesis of Rheumatoid Arthritis?
  • 9 General Discussion: Mycobacterium Leprae Specific Activation of Helper and Suppressor T Cells and its Regulation by HLA Class II Genes and Products
  • Short Summary