Strategic Medical Science Against Brain Attack

The importance of the therapeutic time window for ischemic stroke has been widely accepted for a long time. Consequently, I have been thinking about the past, when the term "brain attack," which was reimported from the United States, began to spread by repetition. In the 1980s, I had made...

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Bibliographic Details
Other Authors: Kikuchi, H. (Editor)
Format: eBook
Language:English
Published: Tokyo Springer Japan 2002, 2002
Edition:1st ed. 2002
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1. Strategies using neuritic reconstruction and neuroregeneration
  • Neural stem cells as a tool for cell transplantation
  • Repair of mammalian central nervous pathways: attempts to reconstruct normal neural connetions with marked functional recovery
  • 2. Strategies of neuroprotection
  • The MEK/ERK pathway as a target for stroke therapy
  • Redox regulation in neuronal damage during brain ischemia—The role of thioredoxin in ischemic neuronal death
  • Structure and functions of pituitary adenylate cyclase activating polypeptide (PACAP) as a neurotrophic factor
  • Neurite outgrowth-promoting prostaglandins that act as neuroprotective agents against brain ischemia and may enhance recovery of higher neuronal functions
  • 3. Strategies using survival or death signals in neurons
  • Molecular mechanisms of neuronal survival; Roles of kinases in ischemic cell death
  • Gene expression and manipulation in injured neurons
  • 4. Strategies for and from cortical spreading depression
  • Cerebral vasospasm induced by the interaction between macrophage and oxidized membrane of erythrocyte
  • 7. Developments in brain-imaging technology
  • Evaluation and analysis of brain attack using MR functional imaging
  • Key Word Index
  • Brain ischemia and spreading depression in a primate model
  • Infarct tolerance induced by repetitive cortical spreading depression is reproduced by prolonged intracerebral infusion of recombinant brain-derived neurotrophic factor
  • 5. Strategies using hypothermia
  • The importance of thermal changes in the pathophysiology of stroke: Post-stroke fever and hypothermia therapy
  • Cerebrovascular disease and hypothermia Part I: Effects of mild hypothermia in the management of cerebrovascular disease
  • Cerebrovascular disease and hypothermia Part II: An experimental approach for ischemic neuronal death
  • Neuroprotection by mild hypothermia for temporary or permanent focal ischemia
  • 6. Strategies for cerebral aneurysm and vasospasm
  • The roles of MMPs for cerebral aneurysm formation
  • Systemically administeredthrombin inhibitors can prevent neointimal formation and cerebral vasospasm: The possible role of thrombin and PDGF-BB in vascular pathogeneses