The Biology of Germinal Centers in Lymphoid Tissue

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hyper...

Full description

Bibliographic Details
Other Authors: Thorbecke, G. Jeanette (Editor), Tsiagbe, Vincent K. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1998, 1998
Edition:1st ed. 1998
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice
  • 2. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts
  • 3. T and B Lymphocytes in Germinal Centers
  • 4. Somatic Hypermutation of Immunoglobulin Genes
  • 5. Germinal Center Derived Lymphomas in Humans and Mice
  • Color Figures