Drug Discovery and Evaluation Pharmacological Assays

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of...

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Bibliographic Details
Other Authors: Vogel, Hans G. (Editor), Vogel, Wolfgang H. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1997, 1997
Edition:1st ed. 1997
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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505 0 |a A Cardiovascular activity -- B Activity on blood constituents -- C Renal activity -- D Respiratory activity -- E Psychotropic and neurotropic activity -- F Drug effects on learning and memory -- G Effects on peripheral nerve function -- H Analgesic, anti-inflammatory, and antipyretic activity -- I Anti-arthrotic and immunmodulatory activity -- J Activity on the gastrointestinal tract -- K Antidiabetic activity -- L Anti-atherosclerotic activity -- M Endocrinology -- N Guidelines for the care and use of laboratory animals 
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653 |a Pharmacology 
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520 |a This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals