Experimental and Clinical Effects of L-Asparaginase International Symposium of Experimtal and Clinical Effects of L-Asparaginase, Wuppertal-Elberfeld 1969

Bibliographic Details
Other Authors: Grundmann, E. (Editor), Oettgen, H.F. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1970, 1970
Edition:1st ed. 1970
Series:Recent Results in Cancer Research
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Opening Remarks
  • I. L-Asparaginase and the Asparagine Metabolism
  • Asparaginase and Cancer — Yesterday and Today
  • L-Asparaginase: Early Findings and Current Studies on the Metabolism of L-Asparagine in Lymphoma Cells
  • Studies on the Control of Asparagine Biosynthesis in Mamalian Tissues
  • II. Preparative Aspects
  • Isolation and Crystallisation of L-Asparaginase from E. coli
  • Biochemical Characterization of L-Asparaginases from E. coli
  • Some Physicochemical Aspects of L-Asparaginase Therapy
  • III. Pharmacokinetics
  • The Distribution and Clearance of L-Asparaginase
  • Pharmacokinetic Behavior of L-Asparaginase in Men and in Animals
  • The Partitioning of L-Asparaginase between Blood and Lymph
  • Critical Influence of an Enzyme-Elevating Virus upon Long-Term Remissions of Mouse Leukemia Following Asparaginase Therapy
  • IV. Experimental Effects
  • Experimental Studies with L-Asparaginase in Mouse Leukemias
  • VII. Clinical Effects and Side Effects
  • Treatment of Acute Leukemia with L-Asparaginase
  • Clinical Experience with L-Asparaginase
  • Clinical Experience with L-Asparaginase
  • Results of a Cooperative Study with L-Asparaginase in Human Leukemias. Report of the Section “Oncology” of the Paul-Ehrlich-Society for Chemotherapy
  • Clinical Experience with L-Asparaginase
  • Treatment of Acute Leukemia with L-Asparaginase — Preliminary Results on 84 Cases
  • The Place of the L-Asparaginase in the Treatment of Acute Leukemias
  • With Reference to Blastogenesis Inhibition by L-Asparaginase
  • Some Clinical Observations on the Treatment with L-Asparaginase of the Acute Leukemias
  • Clinical Trials of Asparaginase in Chemotherapy-Resistant Acute Leukemias
  • Use of Asparaginase in Conjunction with Cytosine Arabinoside in Acute Leukemia in Children
  • Clinical Studies with L-Asparaginase in Dermatomyositis
  • Blood Coagulation Changes under L-Asparaginase Therapy
  • Experimental Investigations on Problems of the Clinical Use of L-Asparaginase
  • Studies on the Glutaminase Activity of E. coli Asparaginase in Tissue Culture
  • L-Asparaginase in the Treatment of Neoplastic Diseases of the Dog, Cat and Cow
  • The Cytomorphological Effects of L-Asparaginase in Sensitive Cells
  • Inhibitation by L-Asparaginase from E. coli of Human Malignant Melanoma Cells Growing in vitro
  • Influence of L-Asparaginase Preparations of E. coli and Agouti Serum on the Homograft Reactivity in the Mouse
  • Studies on the Immunosuppressive Activity of L-Asparaginase
  • Experimental Immunosuppression with L-Asparaginase
  • V. Animal Toxicity
  • Experimental Studies on the Toxicity of Crasnitin in Animals
  • VI. Resistance Problems
  • The Effect of Asparaginase on Some Animal-Tumors
  • Studies of Resistance to L-Asparaginase in Human Leukemia
  • The Antigenicity of E.coli-Asparaginase
  • Studies on Antibody Formation in Patients Treated with L-Asparaginase
  • The Hemostatic Defect Induced by Treatment with Asparaginase in Leukemia
  • Dysmetabolic and Neurological Complications in Leukemic Patients Treated with L-Asparaginase
  • A Summary of the Clinical Status of Asparaginase