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Comparative Mammalian Cytogenetics An International Conference at Dartmouth Medical School Hanover, New Hampshire, July 29–August 2, 1968

Ten years ago a symposium on Cytotaxonomy 'was held in London (Proc. Linn. Soc. Lond. 169:110, 1958) in which a first attempt was made to bring together various disciplines to discuss advances of mammalian cytogenetics and to put them into proper context with the sciences of evolution and taxon...

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Bibliographic Details
Other Authors: Bernischke, Kurt (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1969, 1969
Edition:1st ed. 1969
Subjects:
Cytogenetics
Medicine/public Health, General
Medicine
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Other types of translocation in humans
  • Lethal Chromosome Errors
  • General considerations of lethal genetic errors
  • Abortion studies in man
  • Polyploidy
  • Recognized abortions in man, trisomies
  • Effects of triploidy, hydatidiform moles
  • Semilethal errors
  • XO anomaly
  • Conclusions
  • Meiosis in Mammals
  • Studies at pachytene
  • Chiasmata
  • Structural changes
  • Inversion
  • Duplication and deficiency
  • Reciprocal translocation
  • Robertsonian translocation
  • Insertion
  • Summary
  • Hybrid Sterility
  • Cattle × Bison hybrids (Cattalos)
  • Chicken × Pheasant hybrids
  • Electronmicroscopic studies
  • Teratological results
  • Summary
  • Experimental Hybridization
  • Fertilization and prenatal development
  • Peromyscus
  • Goat-sheep
  • Ferret-mink
  • Rabbit-hare
  • Chromosome studies
  • Hybrids reaching adult life
  • Hybrids which die during pregnancy
  • Ferret × mink
  • Rabbit × snowshoe hare
  • Discussion
  • Summary
  • Genetic Aspects of Infertility
  • Review of normal development
  • Theories and experiments relating to mammalian sex differentiation
  • Cases 1–4
  • Discussion
  • Position of male determinators on Y
  • Extragenital function of Y
  • Testicular tissue in XX individuals
  • Function of second X in females
  • Summary
  • Anomalies of Sex Chromosomes in Tortoiseshell Male Cats
  • and nomenclature
  • Report of two cases
  • Summary of reported cases
  • Theories of pathogenesis
  • Meiotic non-disjunction
  • Polyandry; suppression of polar body; fusion
  • Failure of second meiotic division
  • Abnormal syngamy; initial triploidy
  • Fusion of zygotes
  • Exchange of cells between twins
  • Summary
  • Aneuploidy, Polyploidy and Structural Rearrangement of Chromosomes in Mammals Other Than Man
  • General introduction
  • Terminology
  • Timing of errors in development
  • Polyploidy
  • Findings in domestic animals
  • Chimerism
  • Possible causative factors of aneuploidy
  • Voucher Specimens in Comparative Cytogenetic Studies
  • Findings and conclusions
  • Summary
  • Cytogenetics of Marsupials
  • Chromosome number in the marsupialia
  • General
  • Marsupials with 2n = 14
  • Marsupials with 2n other than 14
  • Conclusions
  • Autosomal chromosomal polymorphism
  • Sex chromosomes in the marsupials
  • Sex determination in the marsupials
  • Multiple sex chromosome systems
  • The XX/XY sex chromosome systems in marsupials
  • Sex chromosome mosaicism
  • Marsupials as animals for genetic research
  • Insectivore Cytogenetics
  • General considerations
  • Macroscelidae
  • Talpidae, Erinaceidae
  • Soricidae
  • Tenrecidae
  • Solenodontidae
  • Tupaiidae
  • Comments and Summary
  • Cytologic Mechanisms of Karyotype Evolution in Insectivores
  • General introduction
  • Talpidae
  • Erinaceidae
  • Robertsonian polymorphism in genus Mus
  • Concluding remarks
  • Summary
  • Patterns of Autosomal Heterochromatin
  • General remarks
  • Methodology—Erinaceidae
  • Nuclear chromatin findings
  • Tritiated thymidine labeling
  • Classical taxonomic considerations
  • Handling of animal identification by cytogeneticist
  • Deposition of specimens with museum collections
  • Obligations of investigators, curators and editors
  • Concluding Remarks: Where Do We Go From Here?
  • Summary of Conference
  • Technical Addendum
  • Bone Marrow Preparations for Chromosome Studies
  • Collection in field
  • Direct bone marrow preparations
  • Short-term bone marrow cultures
  • Fixation
  • Air-dried preparations
  • Squash preparations
  • Meiotic Preparations from Mammalian Testes
  • Schedule
  • Comments
  • A Combined Toluidine Blue Stain and Mounting Medium
  • General Technique
  • General considerations
  • Anatomical malformations causing infertility
  • Abnormalities in gametes
  • Embryonic mortality and lethal genes
  • Maternal effects
  • Genetic indicators of infertility
  • Other genetic variations in fertility; summary
  • Gene Action in Human Diploid Cell Strains
  • Gene action
  • Cellular differentiation
  • Relationship of method of obtaining variant cells to the cell type employed
  • Genetic markers in human diploid cell cultures
  • The single active X-theory
  • Some examples of gene action in human diploid cell strains
  • The Lesch-Nyhan syndrome
  • Hurler’s syndrome
  • Orotic aciduria
  • The theory of intercellular complementation
  • Summary
  • Chromosome Mosaics as Markers in Embryology
  • Distribution of cells in XY/XXY mosaic embryo
  • Possible origin of mosaic
  • Embryologic consequences
  • Consequences for Lyon hypothesis
  • Summary
  • Multipolar Mitosis and Somatic Segregation in Cell Cultures of Microtus Agrestis
  • Tissue culture system
  • Species, Speciation, and Chromosomes
  • The species concepts
  • Reproductive isolation and chromosomal mutation
  • The bottleneck of heterozygosity
  • Mechanisms of Chromosomal Changes in Mammalian Speciation
  • General introductio
  • Numerical changes
  • The Robertsonian process
  • Non-Robertsonian changes
  • The Mammalian Genome in Evolution and Conservation of the Original X-Linkage Group
  • Importance of karyotypic differences
  • Conservation of X-linkage
  • Homology between non-homologues
  • Summary
  • Geographic Variation of Chromosome Forms in Spalax, a Subterranean Mammal of Restricted Mobility
  • Distribution of Spalax, mole rats
  • Identification of different karyotypes
  • Mechanisms of chromosomal changes in Spalax
  • Consideration of reproductive isolation
  • Summary
  • Induced Chromosomal Aberrations with Special Reference to Man
  • General considerations of mutagenesis
  • Cytological changes
  • LSD effects
  • Human “centric fusion” changes
  • Metaphase spread correlations
  • Autosomal heterochromatin in meiosis
  • General conclusions
  • Chromosomal Evolution in Rodents
  • Chromosomal rearrangements
  • Chromosome polymorphism
  • Speciation and chromosomal diversity
  • Hybridization
  • Sex chromosomes
  • Cytotaxonomy
  • Summary
  • Cytogenetic and Phylogenetic Studies in Carnivora
  • Phylogenetic considerations of carnivores
  • Marker chromosomes
  • Canidae
  • Mustelidae
  • Felidae
  • Viverridae
  • Karyotype evolution
  • Cytogenetic Studies of Some Armadillos
  • Dasypus
  • Euphractus
  • Chaetophractus
  • Cabassous
  • Discussion
  • Summary
  • Addendum (Priodontes)
  • Artiodactyl Mammals: Their Chromosome Cytology in Relation to Patterns of Evolution
  • Suiformes
  • Tylopoda
  • Ruminantia
  • General discussion
  • Sex chromosomes
  • Perspectives
  • Primates
  • General discussion
  • Methodology
  • Prosimii
  • Platyrrhini
  • Catarrhini
  • Chromosomal evolution
  • Summary
  • Considerations of Sex Chromosome Abnormalities in Man

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