Transgenic Models of Human Viral and Immunological Disease

Most diseases are multifactoral. Transgenic technology permits gene(s) of interest to be expressed in a small manipulatable laboratory animal model. By this process, murine models of human infections can be developed and studied; effects of cytokines in vivo, focally expressed in unique cells can be...

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Bibliographic Details
Other Authors: Chisari, Francis V. (Editor), Oldstone, Michael B.A. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1996, 1996
Edition:1st ed. 1996
Series:Current Topics in Microbiology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Cytotoxic T Cell Effector and Memory Function in Viral Immunity
  • Transgenic Mouse Models of Experimental Autoimmune Encephalomyelitis
  • The Contribution of Insulitis to Diabetes Development in Tumor Necrosis Factor Transgenic Mice
  • Influence of T Lymphocytes and Major Histocompatibility Complex Class II Genes on Diabetes Susceptibility in the NOD Mouse
  • Virus-Induced Autoimmune Disease: Transgenic Approach to Mimic Insulin-Dependent Diabetes Mellitus and Multiple Sclerosis
  • Role of HLA-B27 in Spondyloarthropathies
  • The Influence of Cytokines on the Central Nervous System of Transgenic Mice
  • Mx Transgenic Mice - Animal Models of Health
  • Hepatitis B Virus Transgenic Mice: Models of Viral Immunobiology and Pathogenesis
  • Transgenic Models of HTLV-I Mediated Disease and Latency
  • Transgenic Models of Human Immunodeficiency Virus Type-1
  • Transgenic Models in the Study of AIDS Dementia Complex
  • Regulation of Expression and Pathogenic Potential of Human Foamy Virus In Vitro and in Transgenic Mice
  • Transgenetics of Prion Diseases
  • Poliovirus Biology and Pathogenesis
  • Safety Requirements for Maintenance and Distribution of Transgenic Mice Susceptible to Human Viruses: The Example of Poliovirus-Susceptible Transgenic Mice