Activation and Desensitization of Transducing Pathways

Activation by and desensitization to signals originating from the environment is common in all organisms, ranging from prokaryotes to higher eukaryotes. Recently, a number of novel mechanisms involved in activation and desensitization have been elucidated. The similarities of the molecular mechanism...

Full description

Bibliographic Details
Other Authors: Konijn, T.M. (Editor), Houslay, M.D. (Editor), Haastert, P.J.M. van (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1990, 1990
Edition:1st ed. 1990
Series:Nato ASI Subseries H:, Cell Biology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Regulation of the desensitization of the acetylcholine nicotinic receptor
  • Cellular Systems
  • The control of human thyroid cell function, proliferation and differentiation
  • Activation of the regulated secretory pathway in neuronal cells during in vitro differentiation
  • Chemotaxis and Chemosensing
  • Activation and desensitization in bacterial Chemotaxis
  • Adaptation of chemoattractant elicited responses in Dictyostelium discoideum
  • The inositolcycle of Dictyostelium discoideum
  • Cyclic Nucleotide-Coupled Systems
  • Glucagon activates two distinct signal transduction systems in hepatocytes,which leads to the desensitization of G-protein-regulated adenylate cyclase, the phosphorylation and inactivation of Gi-2 and the phosphorylation and stimulation of a specific cyclic AMP phosphodiesterase
  • Multiple pathways for glucagon-induced heterologous desensitization of liver adenylyl cyclase
  • The mechanisms of luteinizing hormone-induced activation and desensitization of adenylate cyclase
  • Role of protein kinases in the desensitization-sensitization of ?-adrenergic receptor and prostaglandin receptor stimulation of adenylyl cyclase
  • Direct involvement of the cyclic nucleotide binding sites in the cyclic-nucleotide-induced charge shift of protein kinases
  • Inositol Phospholipid-Coupled Systems
  • Heterogeneity amongst myo-inositol derivatives: metabolism of second messengers and synthesis of co-signals
  • Role of glycosyl-phosphatidylinositols in insulin signaling
  • Agonist and guanine nucleotide regulation of P2Y-purinergic receptor-linked phospholipase C
  • G-Protein Activation
  • Mechanisms involved in G-protein activation by hormone receptors
  • Visual Transduction
  • Regulation and rapid inactivation of the light induced cGMP phosphodiesterase activity in vertebrate retinal rods
  • Auxin-Coupled Systems
  • Characterization and modulation of the sensitivity of plant protoplasts to auxin
  • The auxin-binding-protein from maize coleoptiles
  • Is a GTP-binding protein involved in the auxin-mediated phosphoinositide response on plant cellmembranes?
  • Ion Conductance