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Molecular and Cellular Mechanisms of H+ Transport

Reviewed here is the current knowledge of proton transport mechanisms in mammals. The emphasis is on gastric acid secretion and the role of the H+, K+-ATPase, but molecular and cellular information on other P-, V- and F-type H+-ATPases, in bone, kidney, plants and yeast, as well as other cation ATPa...

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Bibliographic Details
Other Authors: Hirst, Barry H. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1994, 1994
Edition:1st ed. 1994
Subjects:
Cell Biology
Cytology
Biochemistry
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Gastric H+,K+-ATPase
  • Gene Structure and Regulation of Gastric Proton Pump
  • The Gastric H/K ATPase ß Subunit Gene and Transcriptional Pathways in Acid-Secreting Epithelia of the Stomach and Kidney
  • Functional Expression of Gastric H,K-ATPase in Sf9 Cells Using the Baeulovirus Expression System
  • Structural and Functional Integrity of H,K-ATPase Depends on Its ß-Subunit
  • The Topology of the ?, ß Subunits of the Gastric H/K ATPase
  • Synthetic Peptide Antibody Probes of Membrane Orientation of the Gastric H,K-ATPase
  • Molecular Determinants of Subunit Assembly and Processing in Na,K-ATPase and H,K-ATPase
  • Assembly of Hybrid Pumps from Na,K-ATPase ? Subunits and the H,K-ATPase ß Subunit
  • DCCD Inhibition of Cation Binding in the Gastric H,K-ATPase
  • Mapping of a Cytoplasmic Site of Gastric (H+,K+)-ATPase Involved in the Transmission of K+-Activation Across the Membrane
  • H+-Coupled Solute Transport in Cultured Intestinal Epithelia
  • Measurement of H+ and Ca2+ Extrusion from Single Isolated Cells
  • CFTR Chloride Channels and Pancreatic Ductal Bicarbonate Secretion
  • Acute Regulation of Na+:HCO3- Cotransport System in Kidney Proximal Tubules
  • Potassium Dependent H+/HCO3- Transport Mechanisms in Cells of Medullary Thick Ascending Limb of Rat Kidney
  • Regulation of proton and HCO3- transport
  • Characterization of Parietal Cell Functional Morphology Utilizing Isolated Gastric Gland Perfusion, Atomic Force and Confocal Microscopy
  • Activation of Calpain in Gastric Parietal Cells
  • Stimulation of Gastric Acid Secretion Causes Actin Filament Formation and Development of the Secretory Surface in Frog Oxynticopeptic Cells
  • Expression of Rat Gastric H+,K+-ATPase in Insect Cells Using a Double Recombinant Baculovirus
  • Influence of F-Actin on Na+/K+/2CI- Cotransport in Cultured Intestinal Epithelia
  • Structure-Function Relationships in Transmembrane Segment IV of the Yeast Plasma Membrane [H+]-ATPase
  • The Role of Two Small Proteolipids Associated to the H+-ATPase from Yeast Plasma Membrane
  • Ion Translocation Stoichiometries of Two Endomembrane H+-Pumps Studied by Patch Clamp
  • Molecular Dissection of Vacuolar H+-Pyrophosphatase
  • F-type H+-ATPase: Catalysis and Proton Transport
  • Contribution of Infrared Spectroscopy to the Understanding of the Structure of the Neurospora crassa Plasma Membrane H+-ATPase
  • Partial Reaction Chemistry and Charge Displacement by the Fungal Plasma-Membrane H+-ATPase
  • Proton/anion antiports, symports and channels
  • Molecular Properties, Kinetics and Regulation of Mammalian Na+/H+ Exchange
  • Polarized Na/H Exchangers in Colonic Epithelium: A Problem of Balance
  • The AE Gene Family of Band 3-Related Anion Exchangers
  • Proton-Coupled Peptide Transport in the Small Intestine and Kidney
  • Ca2+ Pools and H+ Secretion by the Parietal Cell
  • Acidophylie Cl- and K+ Channels of the Gastric Parietal Cell: A New Model of Regulated HCl Secretion
  • Uncoupling of H+ and Pepsinogen Secretion in the Amphibian Oxyntopeptic Cell
  • The Canine Gastric Muscularis Mucosae and Acid Secretion: A Basket Case?
  • The Receptors Regulating Acid Secretion On and Off the Parietal Cell
  • Post-Receptor Signaling Mechanisms in the Gastric Parietal Cell
  • Cellular resistance to acid
  • Relative Sensitivity to Acid Injury of Different Regions of the Intestinal Tract
  • “First-Pass” Protection Against Luminal Acid in Necturus Antral Epithelium
  • Regulation of pHi in Oxyntic Cells in Intact Sheets of Frog Gastric Mucosa
  • Oxyntic cell Na+/H+ and CI-/HCO3- exchangers
  • Duodenal Mucosal Bicarbonate Secretion in Humans
  • Gastric Bicarbonate Secretion
  • Role of Dopamine in Control of Duodenal Mucosal Bicarbonate Secretion
  • Author Index
  • New Approaches to Inhibition of Gastric Acid Secretion: Development and Mechanism of Omeprazole
  • K+-Competitive Inhibitors of the Gastric (H + + K+)-ATPase
  • Bioactive Peptide Inhibitors and an Endogenous Parietal Cell Protein: Interactions with the Gastric H+/K+ ATPase
  • The Gastric H/K-ATPase: The Principle Target in Autoimmune Gastritis
  • Non-gastric transport-ATPases
  • Acidic and Non-Acidic Endosomes in Kidney Epithelial Cells: Their Role in Cell-Specific Membrane Recycling Processes
  • Regulation and Properties of the Coated Vesicle Proton Pump
  • Characterization of the Osteoclast Vacuolar H+ ATPase: Biochemistry, Subunit Composition and Cloning of Catalytic Subunits
  • The Renal H-K-ATPase: Function and Expression
  • Apical K+-ATPase and Active Potassium Absorption in the Distal Colon
  • Amino Acid Residues Involved in Ouabain Sensitivity and Cation Binding
  • The Use of Site-DirectedMutagenesis to Identify Functional Sites in the Ca2+ ATPase

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