Transmissible Spongiform Encephalopathies Scrapie, BSE and Related Human Disorders

In spite of a long history of intense investigation the transmissible spongiform encephalopathies remain a poorly understood family of neurodegenerative diseases. This group of diseases has been described in a wide variety of animal species and includes kuru, Creutzfeldt-Jakob disease, and Gerstmann...

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Bibliographic Details
Other Authors: Chesebro, Bruce W. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1991, 1991
Edition:1st ed. 1991
Series:Current Topics in Microbiology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • The Human Spongiform Encephalopathies: Kuru, Creutzfeldt-Jakob Disease, and the Gerstmann-Sträussler-Scheinker Syndrome
  • Bovine Spongiform Encephalopathy
  • Purification of Scrapie Agents: How Far Have We Come?
  • The Scrapie Fibril Protein and Its Cellular Isoform
  • Ultrastructural Studies of Prions
  • In Vitro Expression and Biosynthesis of Prion Protein
  • Prion Protein Genes: Evolutionary and Functional Aspects
  • Scrapie Strain Variation and Its Implications
  • Evidence for Biological and Structural Diversity Among Scrapie Strains
  • Genetics of Prion Diversity and Host Susceptibility
  • Natural Transmission and Genetic Control of Susceptibility of Sheep to Scrapie
  • The Scrapie Agent In Vitro
  • The Scrapie Agent: “A Virus by Any Other Name”
  • Novel Properties and Biology of Scrapie Prions
  • Identifying and Mapping Changes in Gene Expression Involved in the Neuropathology of Scrapie and Alzheimer’s Disease
  • Search for a Transmissible Agent in Alzheimer’s Disease: Studies of Human Buffy Coat