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140122 ||| eng |
| 020 |
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|a 9783642764929
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| 100 |
1 |
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|a Pfeffer, Klaus
|e [editor]
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| 245 |
0 |
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|a Function and Specificity of γ/δ T Cells
|h Elektronische Ressource
|b International Workshop, Schloß Elmau, Bavaria, FRG October 14–16, 1990
|c edited by Klaus Pfeffer, Klaus Heeg, Hermann Wagner, Gert Riethmüller
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| 250 |
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|a 1st ed. 1991
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| 260 |
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|a Berlin, Heidelberg
|b Springer Berlin Heidelberg
|c 1991, 1991
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| 300 |
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|a XII, 296 p
|b online resource
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| 505 |
0 |
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|a Genomic Organization -- Genetic Organization of Human T Cell Receptor Gamma Locus. -- Differentiation In Vitro -- Development of Human T Cells Expressing TCR?? In Vitro -- From the Development Expression of ?? T Cell Receptors to the Implications in the Aquisition of Tolerance -- Culture Conditions Dictate Whether Mouse Fetal Thymus Lobes Generate Predominantly ?/? or ?/? T Cells -- Preferential Development of ?/?-Bearing T Cells in Athymic Nude Bone Marrow -- Developmentally Ordered Expression of ?? TCR V?7 Subfamily Genes -- Maturation/ Selection -- Tissue Distribution and Repertoire Selection of Human ?? T Cells: Comparison With the Murine System -- Evidence For Controlled Gene Rearrangements and Cytokine Production During Development of Human TCR??+ Lymphocytes -- Thymic and Extrathymic Development of Human ?/? T Cells -- Differential Effects of Anti-CD3 Antibodies In Vivo and In Vitro on ?? and ?? T Cell Differentiation --
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| 505 |
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|a The Beginning and the End of the Development of TCR?? Cells in the Thymus -- Cyclosporin A (CsA) Prevents the Generation of Mature Thymic ?/? T Cells but Spares ?/? T Lymphocytes. -- Other Species -- Lack of Alloantigen-Specific Cytotoxic T Cell Activity in the TCR?? T Cell Subpopulation of Alloantigen-Immune Chickens -- Thymic Nurse Cells: A Site for Positive Selection and Differentiation of T Cells -- Marked Variations in ?? T Cell Numbers and Distribution Throughout the Life of Shepp -- ?/? T-Lymphocyte Subsets in Swine -- Transgenic Mice/Manipulation In Vivo -- Mechanisms of Development of ?? T Cell Antigen Receptor-Bearing Cells in ?? T Cell Antigen Receptor Transgenic Mice -- Ligand Specificity and Repertoire Development of Murine TCR?? Cells -- Antigen/ Heat Shock Proteins -- Specificity of Mycobacteria/Self-Reactive ??Cells -- Modulation of Murine Self Antigens by Mycobacterial Components. --
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| 505 |
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|a Antigens and Antigen-Presenting Molecules for ?? T Cells -- Correlation Between TCRV Gene Usage and Antigen Specificities in Human ?? T Cells -- Qa-1 Restricted ?? T Cells Can Help B Cells. -- CD5 B Cells -- CD5 B Cells in the Mouse -- Mucosal and Dermal Immunity -- Selection ofV?4+T Cell Receptors of Intestinal Intraepithelial Lymphocytes is Dependent on Class II Histocompatibility Antigen Expression. -- The Role of Fetal Epithelial Tissues in the Maturation/Differentiation of Bone Marrow-Derived Precursors into Dendritic Epidermal T Cells (DETC) of the Mouse -- Phenotypic and Functional Characterization of Human TCR??+ Intestinal Intraepithelial Lymphocytes. -- A Search for Cells Carrying the ?/? T Cell Receptor in Mice Infected withLeishamia major -- Involvement of ?? T Cells in Respiratory Virus Infections
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| 505 |
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|a In Vitro Activation of Human ?/? T Cells by Bacteria: Evidence for Specific Interleukin Secretion and Target Cell Lysis. -- A Dichotomy Between the Cytolytic Activity and Antigen-Induced Proliferative Response of Human ?? T Cells -- Analysis of Primary T Cell Responses to Intact and Fractionated Microbial Pathogens. -- function and Specificity of Human V?9/V?2 T Lymphocytes -- Daudi Cell Specificity Correlates With the Use of aV?9-V?2 Encoded TCR?? -- TCT.1: ATarget Structure for a Subpopulation of Human ?/? T Lymphocytes. -- Activation and Deactivation of Cloned ?/? T Cells -- ?? T Cells in Leprosy Lesions -- Modifications of ?? T Lymphocytes in the Rheumatoid Arthritis Joint -- Phenotypic and Functional Heterogeneity of Double Negative (CD4-CD8-) ?? TcR+T Cell Clones -- Restriction -- Specificity of Human T Lymphocytes Expressing a ?/? T Cell Antigen Receptor. Recognition of a Polymorphic Determinant of HLA Class I Molecules by a ?/? Clone --
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| 653 |
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|a Cell Biology
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| 653 |
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|a Cytology
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| 653 |
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|a Immunology
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| 653 |
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|a Allergy
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| 653 |
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|a Medical Microbiology
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| 653 |
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|a Allergology
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| 653 |
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|a Medical microbiology
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| 700 |
1 |
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|a Heeg, Klaus
|e [editor]
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| 700 |
1 |
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|a Wagner, Hermann
|e [editor]
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| 700 |
1 |
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|a Riethmüller, Gert
|e [editor]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 490 |
0 |
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|a Current Topics in Microbiology and Immunology
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| 028 |
5 |
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|a 10.1007/978-3-642-76492-9
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-642-76492-9?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 6,169,041
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| 520 |
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|a Our current understanding of a/~ T cell receptor (TCR) ex pressing T cells advanced from function and specificity to the molecular organization ofthe TCR.We now know that the TCR a and ~ chains together express specificity for (antigenic) peptides presented by the "responder" M H C allele, thus explain ing the phenomenon of MHC restriction at a molecular level. Surprisingly even though our perception of the molecular organization of the y5 TCR is well advanced, current knowledge of function and specificity of the y5 T cell subset is poor. There fore it appeared rather timely to bring together scientists pioneering research on y5 T cells forthe International Workshop on Function and Specificity ofy5 Tcells,held October11-14, 1990 at Schloss Elmau/Bavaria, FRG. Besides offering a scientific forum for open discussions, it was also hoped that such a workshop would be seminal for collaborative interactions and personal relationships among scientists "addicted" to y 15 T cells
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