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140122 ||| eng |
| 020 |
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|a 9783642758652
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| 100 |
1 |
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|a Fisher, James W.
|e [editor]
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| 245 |
0 |
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|a Biochemical Pharmacology of Blood and Bloodforming Organs
|h Elektronische Ressource
|c edited by James W. Fisher
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| 250 |
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|a 1st ed. 1992
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| 260 |
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|a Berlin, Heidelberg
|b Springer Berlin Heidelberg
|c 1992, 1992
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| 300 |
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|a XVI, 587 p
|b online resource
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| 505 |
0 |
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|a 9 Arachidonic Acid Metabolism Platelets and Thromboembolic Disease -- A. Arachidonic Acid Metabolism -- B. Thromboembolic Disease -- C. Concluding Comments -- References -- 10 Chemical Agents That Inhibit Platelet Aggregation -- A. Introduction -- B. Platelet Physiology -- C. Platelet Structure -- D. Platelet Involvement in Thrombosis -- E. Platelet Responses -- F. Inhibition of Platelet Aggregation -- G. Conclusions -- References -- 11 Anticoagulants, Antithrombotic and Thrombolytic Agents -- A. Anticoagulants -- B. Thrombolytic Therapy -- C. Antithrombotic Therapy -- References -- 12 Granulocyte-Macrophage Growth Factors -- A. Introduction -- B. Historical Background -- C. Growth Factors -- D. Other Interleukins -- E. Inhibitors -- F. Cellular Production and Networking -- G. Microenvironment -- H. Conclusions -- References -- 13 Chemical Agents Which Suppress Myelopoiesis: Agranulocytosis and Leukemia -- A. Introduction -- B. Normal Marrow Cell Kinetics --
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| 505 |
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|a 1 Introduction -- 2 Fundamental Control of Hematopoiesis -- A. Introduction -- B. Hierarchical Organization of Hematopoietic Cells -- C. Assay and Characterization of In Vitro Clonogenic Cells -- D. Use of In Vitro Clonogenic Cell Assays -- E. Newer Assays for More Primitive Cells -- F. Regulatory Mechanisms -- G. Future Outlook -- References -- 3 Kidney Regulation of Erythropoietin Production -- A. Introduction -- B. Model for the Control of Erythropoietin Production -- C. Hypoxia and Erythropoietin Production -- D. Adenosine and Erythropoietin Production -- References -- 4 The Mechanism of Action of Erythropoietin: Erythroid Cell Response -- A. Introduction -- B. Model Systems for Studying the Interaction of Erythropoietin with Erythroid Progenitor Cells -- C. Interaction of Other Growth and Development Factors with Erythroid Progenitor Cells -- D. The Erythroid Differentiation Program -- E. Signal Transduction in Erythroid Progenitor Cells --
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| 505 |
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|a F. Erythropoietin as a Competence or Progression Factor -- G. Conclusion -- References -- 5 The Arachidonic Acid Cascade and Erythropoiesis -- A. Introduction -- B. Evidence for the Roles of Arachidonic Acid Metabolism in Erythropoiesis -- C. Future Directions for Research -- References -- 6 Iron Deficiency and Megaloblastic Anemias -- A. Iron-Deficiency Anemia -- B. Megaloblastic Anemias -- References -- 7 Erythropoietin in the Anemia of End-Stage Renal Disease -- A. Assay of Erythropoietin -- B. Pathogenesis of the Anemia of Chronic Renal Failure -- C. Kidney Production of Erythropoietin -- D. Erythropoietin in Therapy of Renal Anemia -- E. Conclusions -- References -- 8 Humoral Control of Thrombocytopoiesis -- A. Introduction -- B. Model for Megakaryocytopoiesis -- C. Controlling Factors -- D. Other Factors Affecting Thrombocytopoiesis -- E. Clinical Aspects of Thrombopoietin -- F. Future of Thrombopoietin -- References --
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| 505 |
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|a C. Pathophysiologic Mechanisms for Drug-Induced Neutropenia -- D. Neutropenia Associated with Cytotoxic Chemotherapeutic Agents -- E. Drug-Induced Myeloid Suppression -- F. Idiosyncratic Neutropenias -- G. Pseudoneutropenia -- H. Secondary Leukemia -- J. Conclusions -- References -- 14 Drugs Useful in the Chemotherapy of the Acute Leukemias -- A. Introduction -- B. Antimetabolites -- C. Drugs that Intercalate in DNA -- D. Podophyllotoxin Derivatives -- E. Vinca Alkaloids -- F. Alkylating/DNA Binding Agents -- G. Adrenal Glucocorticoids -- H. Enzymes -- J. Multidrug Resistance -- References
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| 653 |
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|a Hematology
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| 653 |
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|a Nephrology
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| 653 |
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|a Human Physiology
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| 653 |
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|a Human physiology
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| 653 |
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|a Endocrinology
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| 653 |
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|a Pharmacology
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 490 |
0 |
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|a Handbook of Experimental Pharmacology
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| 028 |
5 |
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|a 10.1007/978-3-642-75865-2
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-642-75865-2?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 615
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