The Molecular Biology of Autoimmune Disease
Autoimmune diseases are common and often associated with considerable morbidity or - in diseases such as IDDM, myasthenia gravis and multiple sclerosis - mortality. In this volume, experts of international stature in basic science and clinical medicine with a common interest in understanding the nor...
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1990, 1990
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| Edition: | 1st ed. 1990 |
| Series: | Nato ASI Subseries H:, Cell Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Session VII Immunogenetics and Autoimmunity
- HLA Class II Sequence Polymorphism and Autoimmunity
- HLA-DQ and Diabetes Mellitus: A Genetic and Structural Paradigm for Models of Disease Susceptibility
- A Single, Recessive, Non-MHC Diabetogenic Gene Determines the Development of Insulitis in NOD Mice
- Autoimmunity — More Than the MHC?
- Chairman’s Summing up
- Session VIII Clinical and Experimental Autoimmunity
- The Idiotypic Network in Experimental Autoimmune Thyroiditis (EAT): Towards a New Conception of Autoimmune Reactivity
- Factors Affecting Diabetes in Rodent Models of Insulin-Dependent Diabetes Mellitus
- Cells and Immune Processes Contributing to Pancreatic Islet Inflammation
- Synopsis of Paper Entitled: “Ir Gene Expression, Antigen Processing and Auto-Antigen Characterisation in Autoimmune Diseases of the Nervous System
- Mechanisms of Resistance to Autoimmune Disease Induced by T Cell Vaccination
- Session IX Clinical and Experimental Autoimmunity II
- T Cell Reactivity to Acetylcholine Receptor in Myasthenia Gravis
- Type I Diabetes as a “Mendelian” and “Regulated” Immune Process
- The Cloning Road to The TSH Receptor and Autoimmune Graves’ Disease
- Thyroid Peroxidase: Studies on Autoantibody Recognition, Gene Expression and Secondary Structure Prediction
- Session X ESCI Boerhaave Lecture for 1989
- Sjogren’s Syndrome, a Model to Study Autoimmunity and Malignancy
- Molecular Genetics of Two Major Thyroid Auto-Antigens: Thyroglobulin and Thyroperoxidase
- Analysis of Auto-Antigenic Determinants of Thyroid Peroxidase Antigen, Generated Using Polymerase Chain Reaction
- Glycolipid Antigens in Type I Diabetes Mellitus and Its Long Term Complications
- On the Main Immunogenic Region of the Acetylcholine Receptor; Structure and Role in Myasthenia Gravis
- Acetylcholine Receptor-Expressing Fibroblasts
- Session V Antigen Processing and Presentation
- The Interaction between MHC Class II Molecules and Immunogenic Peptides
- Molecular Mimicry between Virus Proteins and Autoantigens in Autoimmunity
- Session VI Interaction of Auto-Antigen, MHC and T Cell Receptor
- The Advantages of Limiting the T Cell Repertoire for Antigen and MHC
- Functional Dissociation of T Cell Sites: Immunogenic, Antigenic and Pathogenic Sites
- Autoreactive Cloned T CellLines in Murine Insulin-Dependent Diabetes Mellitus
- Chairman’s Summing up
- Session I Structure and Function of Immunoglobulins and Their Genes
- Organisation and Expression of Human VH Genes
- Immunoglobulin Kappa Variable Gene Segment Usage during Ontogeny
- Session II Structure and Function of the T Cell Receptor and Its Genes
- Molecular Analysis of T Lymphocyte Recognition
- T Cell Development in T Cell Receptor Transgenic Mice
- Target Sequences and Accessibility for Chromosomal Translocations Involving T Cell Receptor Genes
- Session III Structure and Function of the MHC and Its Genes
- Structure of Human Major Histocompatibility Complex Class II Genes
- Dissection of the Roles of Specific Class II Antigens and Accessory Molecules in Antigen Presentation
- The Fine Specificity of Recognition of Influenza Virus Proteins by Human Cytotoxic T Cells
- Chairman’s Summing up Evolutionary Analysis of HLA Class II Polymorphisms
- Session IV Auto-Antigen Characterisation