The Third Component of Complement Chemistry and Biology

The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio­ nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, an...

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Bibliographic Details
Other Authors: Lambris, John D. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1990, 1990
Edition:1st ed. 1990
Series:Current Topics in Microbiology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Participation of C3 and Its Ligands in Complement Activation
  • Biosynthesis and Genetics of C3
  • Molecular Aspects of C3 Interactions and Structural/Functional Analysis of C3 from Different Species
  • The Thioester Bond of C3
  • Complement Receptor Type 1 (C3b/C4b Receptor; CD35) and Complement Receptor Type 2 (C3d/Epstein-Barr Virus Receptor; CD21)
  • The Leukocyte Cell Surface Receptor(s) for the iC3b Product of Complement
  • Decay-Accelerating Factor and Membrane Cofactor Protein
  • Factor H
  • C3 Binding Proteins of Foreign Origin
  • Structure and Function of C3a Anaphylatoxin
  • Molecular Modeling of C3 and Its Ligands
  • C3 Deficiencies
  • Structural and Functional Analysis of C3 Using Monoclonal Antibodies