Glucagon III
Glucagon III complements Glucagon I and II published in 1983 in this series as Vols. 66/I and II. These three volumes truly represent a "glucagon encyclopedia" and as such have no competitors in the scientific literature worldwide. In this volume, the most recent data on glucagon molecular...
| Other Authors: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1996, 1996
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| Edition: | 1st ed. 1996 |
| Series: | Handbook of Experimental Pharmacology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- H. Human Glucagon Receptor
- I. Conclusions
- References
- 5 Mode of Action of Glucagon Revisited
- A. Introduction
- B. Glucagon Actions Mediated Through Glucagon Receptors
- C. Glucagon is Processed by Its Target Cells
- D. Action of Mini-glucagon [Glucagon (19–29)] in Liver
- E. Mini-glucagon Action in Heart
- F. Glucagon and Mini-glucagon Act in Concert
- G. Conclusion and Perspectives
- References
- 6 Pulsatility of Glucagon
- A. Introduction
- B. Oscillations in Glucagon Plasma Levels
- C. Pulsatile Glucagon Secretion In Vitro
- D. Pulsatile Glucagon Delivery In Vitro
- E. Pulsatile Glucagon Delivery In Vivo
- F. Conclusions
- References
- 7 Glucagon and Diabetes
- A. Introduction
- B. Diabetogenic Effects of Glucagon
- C. The A Cell in Diabetes
- D. Circulating Glucagon Levels in Diabetes
- E. Glucagon Dysfunction in Diabetes
- F.Role of Glucagon Excess in the Metabolic Abnormalities of Diabetes
- G. Therapeutic Implications
- H. Conclusions
- 1 The Industrial Production of Glucagon
- A. Introduction
- B. Production
- C. Analysis of Recombinant Human Glucagon
- D. Stability
- References
- 2 The Glucagon Gene and Its Expression
- A. Introduction
- B. Structure
- C. Expression
- D. Conclusions
- References
- 3 Preproglucagon and Its Processing
- A. Introduction
- B. Tissue-Specific Post-translational Processing of Proglucagon
- C. Role of Prohormone Convertases in Proglucagon Processing
- D. Secondary, Postsecretory Processing of Proglucagon-Derived Peptides
- E. Conclusions
- References
- 4 The Glucagon Receptor Gene: Organization and Tissue Distribution
- A. Introduction
- B. Cloning of the Glucagon Receptor
- C. Organization of the Glucagon Receptor Gene
- D. Tissue Distribution of the Glucagon Receptors
- E. Tissue Distribution of Glucagon Receptor Transcripts
- F. Regulation of Glucagon Receptor Gene Expression
- G. Structure/Function Analysis of the Glucagon Receptor
- References
- 8 The Search for Glucagon Antagonists
- A. Glucagon as a Drug Target
- B. Search for a Glucagon Antagonist
- References
- 9 Glucagon and Glucose Counterregulation
- A. Introduction
- B. Glycemic Action of Glucagon
- C. Glucagon Secretion
- D. Role of Glucagon in Glucose Counterregulation
- E. Conclusions
- References
- 10 Modes of Glucagon Administration
- A. Introduction
- B. Classic Routes of Administration
- C. New Routes of Glucagon Administration
- D. Conclusions
- References
- 11 The Place of Glucagon in Emergency Medicine
- A. Hypoglycemia
- B. Cardiovascular Insufficiency
- C. Vascular Effects
- D. Renal/Urologic Effects
- E. Shock
- F. Respiratory Effects
- G. Gastrointestinal Effects
- H. Radiographic Studies
- I. Adverse Effects
- References
- 12 The Place of Glucagon in Medical Imaging
- A. Introduction
- B. Upper Gastrointestinal Tract
- C. Small Bowel
- D. Large Bowel
- E. Biliary Tract
- F. Other Applications
- G. Side Effects and Contraindications
- References
- 13 The Glucagon Test for Evaluation of Insulin Secretion
- A. Introduction
- B. Methodological Aspects
- C. Comparison with Other Stimuli
- D. Clinical Applications
- E. Conclusions
- References
- 14 Glucagon and the Control of Appetite
- A. Introduction
- B. Prandial Glucagon Secretion
- C. Glucagon Administration and Food Intake
- D. Glucagon Antagonism and Food Intake
- E. Mechanism of Glucagon Satiety
- F. Clinical Aspects
- G. Conclusions
- References
- 15 Glucagonoma and Its Management
- A. Introduction
- B. Diagnosis and Localization of the Tumor
- C. Management of the Glucagonoma Syndrome
- D. Prognosis
- E. Conclusions
- References
- 16 Structure and Functionof the Glucagon-Like Peptide-1 Receptor
- A. Introduction
- B. GLP-1 Receptor
- C. Conclusions
- References
- 17 Physiology and Pathophysiology of GLP-1
- A. The Incretin Concept
- B. Origin, Processing, Secretion and Fate of GLP-1
- C. Tissue Distribution of GLP-1 Receptors and Biological Actions
- D. Signal Transduction of the GLP-1 Receptor
- E. Pathophysiological Relevance?
- References
- 18 Potential of GLP-1 in Diabetes Management
- A. Introduction
- B. Actions of GLP-1 on Blood Glucose in Humans
- C. Gastrointestinal Effects of GLP-1 in Humans
- D. GLP-1 and Diabetes
- E. GLP-1 Metabolism in Normal and Diabetic Subjects
- F. Conclusion and Outlook
- References
- 19 Oxyntomodulin and Its Related Peptides
- A. Introduction
- B. Biological Characteristics of Oxyntomodulin
- C. Conclusions
- References