| Summary: | This is the second edition of a monograph which provided a concise approach to an understanding of the spontaneous and induced lesions in the respiratory system of laboratory animals, especially the rat, mouse, and hamster. This expanded edition keeps the basic format of the first edition but provides much more information applicable to the study of toxicologic pathology. For example, the effects of inhaled toxicants of the upper respiratory tract are presented in detail in relation to the specific cells affected, based upon their precise morphology and function discerned at the ultrastructural level. This approach is followed through the entire volume, with precise identification of the cells preceding consideration of perturbations caused by toxicants of other etiologic agents. Current understanding of the nature and significance of pathologic lesions is probed throughout the volume. Although toxicologic pathology is emphasized, experimental pathologists and other scientists will find this book especially useful
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