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140122 ||| eng |
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|a 9783642598845
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| 100 |
1 |
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|a Lestienne, Patrick
|e [editor]
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| 245 |
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|a Mitochondrial Diseases
|h Elektronische Ressource
|b Models and Methods
|c edited by Patrick Lestienne
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| 250 |
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|a 1st ed. 1999
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| 260 |
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|a Berlin, Heidelberg
|b Springer Berlin Heidelberg
|c 1999, 1999
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| 300 |
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|a XII, 396 p
|b online resource
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| 505 |
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|a 1 Organization and Expression of the Mitochondrial Genome -- 2 Mitochondrial DNA Inheritance in Mammals -- 3 Molecular Basis of Mitochondrial DNA Diseases -- 4 Structural Studies on Human Mitochondrial tRNAs -- 5 Structure, Function and Pathology of Complex I -- 6 Complex II or Succinate: Quinone Oxidoreductase and Pathology -- 7 The bc1 Complex in the Mitochondrial Respiratory Chain -- 8 Cytochromec Oxidase and Mitochondrial Pathology -- 9 ATPase-ATPsynthase and Mitochondrial Pathology -- 10 Physiology and Pathophysiology of the Mitochondrial ADP/ATP Carrier -- 11 The Normal and Pathological Structure, Function and Expression of Mitochondrial Creatine Kinase -- 12 Pyruvate Dehydrogenase Deficiencies -- 13 Electrochemical Gradient and Mitochondrial DNA in Living Cells -- 14 A Heteroplasmic Strain of D. subobscura. An Animal Model of Mitochondrial Genome Rearrangement -- 15 Stability of the Mitochondrial Genome of Podospora anserina and Its Genetic Control -- 16 The Control of Ageing and Mitochondria -- 17 Roles of Mitochondria in Apoptosis -- 18 The Triiodothyronine Mitochondrial Pathway -- 19 Cytoskeleton-Mitochondrial Interactions -- 20 NADH Brain Determination by Micromeasurements of a Laser-Induced Fluorescence in the Rat -- 21 Allotopic Expression of Mitochondrial Genes: Further Steps in the Evolution of Eukaryotic Cells and Therapeutic Strategy -- 22 Import of tRNA into Yeast Mitochondria: Experimental Approaches and Possible Applications -- 23 The Import of Cytosolic tRNA into Plant Mitochondria -- 24 Plant Cytoplasmic Male Sterility: A Mitochondrial Pathology and Its Biotechnological Application -- 25 Histopathology of Skeletal Muscle Mitochondria -- 26 Enzymatic and Polarographic Measurements of the Respiratory Chain Complexes -- 27 Mitochondrial DNA Analysis
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| 653 |
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|a Cell Biology
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| 653 |
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|a Medical Genetics
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| 653 |
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|a Medicine / Research
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| 653 |
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|a Cytology
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| 653 |
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|a Biology / Research
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| 653 |
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|a Medical genetics
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| 653 |
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|a Biochemistry
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| 653 |
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|a Biomedical Research
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| 041 |
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|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 028 |
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|a 10.1007/978-3-642-59884-5
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| 856 |
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|u https://doi.org/10.1007/978-3-642-59884-5?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 610.72
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| 520 |
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|a This volume covers the molecular aspects of mitochondrial disorders and their diagnosis with particular emphasis on the mitochondrial tRNA structure and its various mutations. It further describes some key nuclear-encoded proteins involved in energy transduction and presents new aspects of mitochondrial DNA, e.g. its in vivo conformational changes, and models of deletions and partition. Moreover, it discusses the involvement of mitochondria in apoptosis, hormonal response and ageing. This volume also investigates the precise molecular import mechanisms of particular proteins and specific tRNAs into plants and yeast mitochondria relevant to human diseases
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