Signaling Through the Cell Matrix
This book covers a hot subject in cell biology; i.e. how the cell environment sends messages to the cell, regulates gene expression, and modulates the cell phenotype. For a long time the extracellular matrix was believed to have only a supporting role for cell attachement. However, it became apparen...
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2000, 2000
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| Edition: | 1st ed. 2000 |
| Series: | Progress in Molecular and Subcellular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Topological Constraints Carry Signaling from the Cell Matrix to the Genome
- 1 Variation in Cell Adhesion During Proliferation of Normal Cells
- 2 Coupling Between Changes in Cell Adhesion and Proliferation of Transformed Cells
- 3 Mechanisms of Cell Adhesion-Mediated Changes in the Cell Phenotype
- 4 Conclusions
- References
- The Transmission of Contractility Through Cell Adhesion
- 1 Introduction
- 2 Generation of Contractility
- 3 Molecular Mechanism of Force Transmission
- 4 Regulation of Contractility Transmission
- 5 Interaction Between Contraction Force and ECM
- 6 Myofibroblasts and Wound Healing
- 7 Muscle
- 8 Conclusion
- References
- Role of Focal Adhesion Kinase in Signaling by the Extracellular Matrix
- 1 Introduction
- 2 FAK Activation by Integrin
- 3 FAK Downstream Pathways
- 4 Biological Functions of FAK in Signaling by ECM
- References
- 2 Invasion into Matrices
- 3 Effects of Collagen on the Invasive Behavior of Cells
- 4 A Scenario for the Molecular Cross Talk Between Collagen and Cell
- 5 Conclusion
- References
- Interaction Between Cells and Extracellular Matrix: Signaling by Integrins and the Elastin-Laminin Receptor
- 1 Introduction
- 2 Cell-Matrix Interactions Mediated by Integrins
- 3 Cell-Matrix Interactions Mediated by the Elastin-Laminin Receptor
- 4 Discussion and Conclusions
- References
- Regulation of Gene Expression by Changes in Cell Adhesion
- 1 Introduction
- 2 Regulation of Cell Proliferation by Cell Adhesion
- 3 Regulation of Cell Differentiation by Cell Adhesion
- 4 Conclusion
- References
- Expression of Liver Specific-Genes in Hepatocytes Cultured in Collagen Gel Matr
- 1 Introduction
- 2 Culture of Hepatocytes in Collagen Gel
- 3 Hepatic Specific Functions of Hepatocytes in Collagen Cultures
- 4 Biotransformation Capability: Basal and Induced Levels of Drug-Metabolizing Enzymes
- 5 Expression of Hepatic Transcription Factors
- 6 Concluding Remarks
- References
- Collagen Type I: A Substrate and a Signal for Invasion
- 1 Introduction