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140122 ||| eng |
020 |
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|a 9783642586309
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100 |
1 |
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|a Schlag, Günther
|e [editor]
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245 |
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|a Shock, Sepsis, and Organ Failure
|h Elektronische Ressource
|b Scavenging of Nitric Oxide and Inhibition of its Production
|c edited by Günther Schlag, Heinz Redl
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250 |
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|a 1st ed. 1999
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260 |
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|a Berlin, Heidelberg
|b Springer Berlin Heidelberg
|c 1999, 1999
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300 |
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|a XIV, 293 p
|b online resource
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505 |
0 |
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|a Clinical Implication for Sepsis and Congestive Heart Failure -- Inducible NOS and Other Novel Mediators of Inflammation in Brain Trauma -- Nitric Oxide and Leukocyte Adhesion: Experience with NO Inhibitors, NO Donors and iNOS-Deficient Mice -- Cytokine Control of Nitric Oxide Production: Therapeutic Possibilities -- Peroxynitrite: the Dark Side of Nitric Oxide-Effect of Mercaptoethylguanidine (MEG), a Combined Inhibitor of Inducible Nitric Oxide Synthas
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653 |
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|a Emergency medicine
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653 |
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|a Anesthesiology
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653 |
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|a Internal medicine
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653 |
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|a Anesthesiology
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653 |
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|a Internal Medicine
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653 |
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|a Emergency Medicine
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700 |
1 |
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|a Redl, Heinz
|e [editor]
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041 |
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7 |
|a eng
|2 ISO 639-2
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989 |
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|b SBA
|a Springer Book Archives -2004
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856 |
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|u https://doi.org/10.1007/978-3-642-58630-9?nosfx=y
|x Verlag
|3 Volltext
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|a 616
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|a At the Sixth Wiggers Bernard Conference, a group of scientists from various fields discussed new findings relating to nitric oxide synthase inhibitor in shock, sepsis, and organ failure. This meeting was dedicated to the presentation and discussion of positive and negative findings related to the use of NOS inhibitors, the issue of specific and non-specific inhibitors and the role of nitric oxide-oxygen radical interactions. Both experimental and clinical data were presented in the trauma and sepsis field. With appropriate dosing and timing the use of NOS inhibitors seems to be beneficial at least in severe sepsis situations, but some inhibitors and overdosing can be potentially dangerous
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