Microanatomy and Function of the Spleen
This publication provides the first comprehensive review of human splenic microanatomy in correlation with up-to-date information on the immunological function of different splenic compartments. The authors provide an inter-species comparison of splenic microstructure in humans and rats to highlight...
| Main Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2000, 2000
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| Edition: | 1st ed. 2000 |
| Series: | Advances in Anatomy, Embryology and Cell Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 1 Introduction
- 2 Materials and Methods
- 2.1 Animal Spleens
- 2.2 Human Spleens
- 2.3 Antibodies
- 2.4 Single Staining Procedure for Immunohistology
- 2.5 Double Staining Procedure for Immunohistology
- 2.6 Demonstration of Acid Phosphatase in Cryostat Sections
- 2.7 Demonstration of Alkaline Phosphatase in Cryostat Sections
- 3 Microanatomical Compartments of the Rat Spleen
- 3.1 White Pulp
- 3.2 Red Pulp and Splenic Vessels
- 3.3 Summary
- 4 Microanatomical Compartments of the Human Spleen
- 4.1 White Pulp
- 4.2 Red Pulp and Splenic Vessels
- 4.3 Summary
- 5 Function of Splenic Compartments
- 5.1 Splenic White Pulp Compartments during Primary T Cell-Dependent Antibody Responses against Protein Antigens
- 5.2 Function of the Marginal Zone during Primary Antibody Responses against T Cell-Independent Type 2 Antigens
- 5.3 Function of the Red Pulp
- 5.4 Role of the Spleen in CD8+ Cytotoxic T Cell Responses
- 5.5 The Spleen, Natural Killer Cells and Gamma/Delta T Cells
- 6 Recirculation of Lymphocytes Through the Spleen
- 6.1 Summary
- 7 The Role of Cytokines and Chemokines in the Development of Splenic Compartments
- 7.1 Summary
- 8 Unsolved Problems of Human Splenic Structure and Function
- 8.1 Arterial Blood Supply to the Splenic Follicles and to the Perifollicular Zone
- 8.2 Blood Circulation in the Splenic Red Pulp: Subpopulations of Fibroblasts and their Role
- 8.3 Function of Sheathed Capillaries
- 8.4 Lymphocyte Migration in the Human Splenic White Pulp — A Hypothesis
- 9 Summary
- References