TOR Target of Rapamycin
TOR, the Target of Rapamycin was discovered a little over ten years ago in a genetic screen in S. cerevisiae in search of mutants resistant to the cytostatic effects of the anti-mycotic, rapamycin. Since that time orthologues have been identified in all eukaryotes examined to date, including humans....
| Other Authors: | , , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2004, 2004
|
| Edition: | 1st ed. 2004 |
| Series: | Current Topics in Microbiology and Immunology
|
| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- TOR: The First Ten Years
- The Role of Phosphatases in TOR Signaling in Yeast
- Yeast TOR Signaling: A Mechanism for Metabolic Regulation
- Nutrient Signaling Through TOR Kinases Controls Gene Expression and Cellular Differentiation in Fungi
- Autophagy in Yeast: A TOR-Mediated Response to Nutrient Starvation
- The Fission Yeast TOR Proteins and the Rapamycin Response: an Unexpected Tale
- Plant Growth and the TOR Pathway
- TOR Action in Mammalian Cells and in Caenorhabditis elegans
- Genetic Analysis of TOR Signaling in Drosophila
- Interplay Between Growth Factor and Nutrient Signaling: Lessons from Drosophila TOR
- mTOR Signaling to Translation
- Modulation of the Protein Kinase Activity of mTOR
- Role of mTOR Signaling in the Control of Translation Initiation and Elongation by Nutrients
- Novel Regulatory Mechanisms of mTOR Signaling
- Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex
- Kinase Activities Associated with mTOR
- mTOR: A Mediator of Intracellular Homeostasis
- mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia
- Retroviral Oncogenes and TOR
- mTOR as a Target for Cancer Therapy