A Guide to Blood and Marrow Transplantation

This book provides an introduction to marrow and peripheral blood stem cell transplantation (including cord blood transplants), emphasizing the principles of this rapidly evolving area. A brief historical perspective is given and the latest developments are discussed. Particular attention is given t...

Full description

Bibliographic Details
Main Authors: Deeg, H. Joachim, Klingemann, Hans-Georg (Author), Phillips, Gordon L. (Author), Zant, Gary Van (Author)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1999, 1999
Edition:3rd ed. 1999
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
LEADER 03197nmm a2200325 u 4500
001 EB000660145
003 EBX01000000000000000513227
005 00000000000000.0
007 cr|||||||||||||||||||||
008 140122 ||| eng
020 |a 9783642182488 
100 1 |a Deeg, H. Joachim 
245 0 0 |a A Guide to Blood and Marrow Transplantation  |h Elektronische Ressource  |c by H. Joachim Deeg, Hans-Georg Klingemann, Gordon L. Phillips, Gary Van Zant 
250 |a 3rd ed. 1999 
260 |a Berlin, Heidelberg  |b Springer Berlin Heidelberg  |c 1999, 1999 
300 |a XII, 231 p  |b online resource 
505 0 |a I. Pretransplant Considerations -- 1. Rationale and Indications for Transplantation -- 2. Timing of Transplantation -- 3. Stem Cell Sources -- 4. Preparation for Stem Cell Transplantation -- 5. Cost Considerations -- II. Transplant Procedure -- 1. Conditioning Regimens -- 2. Collection and Processing of Stem Cells -- 3. In Vitro Expansion of Stem Cells -- 4. Genetic Manipulation of Hematopoietic Stem Cells -- 5. Prevention and Treatment of Relapse -- III. Transplant-Related Problems -- 1. Side Effects of Conditioning Regimens -- 2. Graft Failure -- 3. Graft-Versus-Host Disease -- 4. Management of Infections -- 5. Single and Multi-Organ Failure -- 6. Chronic Graft-Versus-Host Disease -- 7. Delayed Complications -- IV. Long-Term Follow-Up -- 1. Follow-Up After Discharge from the Transplant Center -- 2. Rehabilitation -- QuoVadis? -- 225 
653 |a Transplantation 
653 |a Hematology 
653 |a Transplantation of organs, tissues, etc 
653 |a Oncology 
700 1 |a Klingemann, Hans-Georg  |e [author] 
700 1 |a Phillips, Gordon L.  |e [author] 
700 1 |a Zant, Gary Van  |e [author] 
041 0 7 |a eng  |2 ISO 639-2 
989 |b SBA  |a Springer Book Archives -2004 
028 5 0 |a 10.1007/978-3-642-18248-8 
856 4 0 |u https://doi.org/10.1007/978-3-642-18248-8?nosfx=y  |x Verlag  |3 Volltext 
082 0 |a 616.15 
520 |a This book provides an introduction to marrow and peripheral blood stem cell transplantation (including cord blood transplants), emphasizing the principles of this rapidly evolving area. A brief historical perspective is given and the latest developments are discussed. Particular attention is given to the rationale and indications for transplantation, the selection of donors and source of stem cells, and the separation, expansion and manipulation of stem cells. Essential aspects of histocompatibility, preparative regimens used in stem cell transplantation, the use of hematopoietic growth factors and cytokines, the pathophysiology of the graft-versus-host reaction, and the management of complications are dealt with. This book should provide the practicing internist, pediatrician, hematologist, and oncologist as well as other physicians in training or in practice, physicians' assistants, nurses, and students with the information necessary to understand the concepts of stem cell transplantation and to include transplantation in the treatment planning soon after a diagnosis has been established. The text should also be useful to the physician who resumes the patients' care when they return from the transplant center