Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during...

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Bibliographic Details
Other Authors: Livrea, Maria A. (Editor)
Format: eBook
Language:English
Published: Basel Birkhäuser 2000, 2000
Edition:1st ed. 2000
Series:Molecular and Cell Biology Updates
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Factors affecting blood levels of vitamin A
  • Enzymology and biogenesis of retinoic acid
  • Requirements and safety of vitamin A in humans
  • Current views on carotenoids: biology, epidemiology and trials
  • The role of vitamin A in visual transduction
  • The role and evolutionary development of retinoic-acid signalling in the eye
  • Vitamin A, retinoids and immune responses
  • Vitamin A and infectious diseases
  • Retinoid metabolism in the embryo
  • Physiologically-based pharmacokinetic scaling in retinoid developmental toxicity
  • Retinoic acid receptors in normal and neoplastic haematopoietic cells
  • Modulation of nuclear vitamin D signalling by retinoids
  • Pharmacology and molecular mechanisms of retinoid action in skin
  • Synthetic retinoids and their usefulness in biology and medicine
  • Proposed role of gap junctional communication in retinoid-induced suppression of proliferation and inhibition of neoplastic transformation
  • Effects of all-trans retinoic acid and 13-cis retinoic acid on breast cancer cell lines
  • Retinoids and interferons: combination studies in human cancer
  • Treatment of acute promyelocytic leukemia with all-trans retinoic acid
  • Bioactivities of N-(4-hydroxyphenyl) retinamide
  • Therapeutic uses of retinoids in skin diseases
  • Retinoid treatment of photoaged skin
  • Therapeutic uses of retinoic acid receptor antagonists and inverse agonists