The Hereditary Basis of Allergic Diseases

Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecula...

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Bibliographic Details
Other Authors: Holgate, Stephen T. (Editor), Holloway, John W. (Editor)
Format: eBook
Published: Basel Birkhäuser 2002, 2002
Edition:1st ed. 2002
Series:Progress in Inflammation Research
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Heredity of allergy and asthma 1
  • Genome scans for asthma
  • The role of founder populations in mapping complex disease genes: Studies in the South Dakota Hutterites
  • Genetic regulation of specific IgE responsiveness
  • Genetic variation at the HLA and TCR loci and the development of allergy and asthma
  • Chromosome 11q13, FccRI13 and atopic asthma
  • Genetic regulation of interleukin-13 production
  • The role of interleukin-9 and the interleukin-9 receptor gene candidates in asthma
  • Genetics of the nitric oxide synthetic pathway in asthma
  • Genetic regulation of leukotriene production and activity
  • Genetics of asthma severity