Macrolide Antibiotics

The current state of research, development, and use of macrolides as a treatment option for bacterial infections is the subject of this monograph. Macrolides, whose first representative (erythromycin) was introduced into the market in the 1950s, have been optimised by various companies into effectiv...

Full description

Bibliographic Details
Other Authors: Schönfeld, W. (Editor), Kirst, H.A. (Editor)
Format: eBook
Language:English
Published: Basel Birkhäuser 2002, 2002
Edition:1st ed. 2002
Series:Milestones in Drug Therapy
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • to the macrolide antibiotics
  • Macrolides: a clinical overview
  • Pharmacokinetics/pharmacodynamics of macrolides
  • Cellular accumulation of macrolide antibiotics. Intracellular bioactivity
  • Clarithromycin and new derivatives of erythromycin
  • Azithromycin and novel azalides
  • Ketolides: novel antibacterial agents designed to overcome resistance to erythromycin A within gram-positive cocci
  • Novel macrolide derivatives active against resistant pathogens
  • Polyketide diversity
  • Biosynthesis of the macrolide antibiotic, tylosin
  • Activity of macrolides against mycobacteria
  • Chlamydia pneumoniae and asthma and atherosclerosis: role of macrolides..
  • Activity of macrolides in sexually transmitted diseases
  • Helicobacter pylori and macrolides
  • Effects of macrolide antibiotics on ribosome function
  • Mechanisms of resistance to macrolides, lincosamides, and ketolides