Peptide Transport and Delivery into the Central Nervous System
Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Basel
Birkhäuser
2003, 2003
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| Edition: | 1st ed. 2003 |
| Series: | Progress in Drug Research
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Neuropeptides: general characteristics and neuropharmaceutical potential in treating CNS disorders
- Structural and functional aspects of the blood-brain barrier
- Peptide transport across the blood-brain barrier
- Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases
- Altering the properties of the blood-brain barrier: disruption and permeabilization
- Modifying peptide properties by prodrug design for enhanced transport into the CNS
- CNS-delivery via conjugation to biological carriers: physiological-based approaches
- Peptide vectors as drug carriers
- Index Vol. 61