Molecular Oncology and Clinical Applications

The basic knowledge of cell biology and molecular genetics in oncology is increasingly attracting the interest of clinical oncologists and is close to reaching a helpful application at the bedside. At present, it seems clear that the solution of the cancer problem lies within the comprehension of th...

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Bibliographic Details
Main Authors: CITTADINI., BASERGA. (Author), PINEDO. (Author), GALEOTTI. (Author)
Format: eBook
Language:English
Published: Basel Birkhäuser 1993, 1993
Edition:1st ed. 1993
Series:Molecular and Cell Biology Updates
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Molecular aspects of cell transformation and growth
  • The Impact of Molecular Genetics on Cancer Research
  • Identification of a Chimeric Gene Frequently Activated in Human Thyroid Papillary Carcinomas
  • The Role of Tumor Suppressor Genes in Human Cancer Progression
  • The Central Role of the IGF-1 Receptor in the Control of Cellular Proliferation
  • Loss of TGF-ß Expression is a Critical Component of Malignant Progression in Multistage Carcinogenesis of the Mouse Epidermis
  • Structure, Biosynthesis and Biochemical Properties of the HGF/SF Receptor
  • Molecular Characterization of Trop-2, a Cell Surface Molecule Highly Expressed by Human Carcinomas — Cloning of the Gene Encoding Trop-2
  • Loss of Heterozygosity and Distribution of Alleles at the VNTR Region of the HRAS Gene in Ovarian Carcinoma
  • Mg2+ in the Regulation of Ascites Tumor Cell Energy Metabolism
  • Effect of Quercetin on Cell Proliferation and Heat Shock Protein Synthesis Induction in K562 Erythroleukemia
  • Pharmacokinetics of Free and Total Platinum Species after Prolonged Venous Infusion of Cisplatin and Concurrent Radiation Therapy for Lung Carcinoma
  • The Role of Interferons in the Treatment of Solid Tumors
  • Endocrine Treatment of Malignant Disease
  • Interactions Between Growth Factors and Oestrogens in Breast Cancer Cells
  • Potentiation of the Antitumor Activity of Tamoxifen by Interferons: A Mini-Review
  • Vitamin E status is Influenced by ?-3 Polyunsaturated Fatty Acid Supplementation in Patients at Risk for Colon Cancer
  • Progress Towards the Clinical Application of Somatic Cell Gene Therapy
  • Intraoperative Radiation Therapy: An Overview
  • Regulation of MnSOD Expression by Manganese in Tumors
  • Membrane receptors and signal transduction
  • An Efficient Expression cDNA Cloning Approach to Screen Human Tumors for Oncogenes
  • The Roles of Specific Isoforms of Protein Kinase C (PKC) in Signal Transduction, Growth Control and Diacylglycerol Metabolism
  • Regulation of Protein Kinase C
  • Potential Roles of p21ras in Growth Factor Signalling — An Overview
  • p21-ras and p56-lck Mediate The Two Major T-Cell Antigen Receptor Signal Transduction Pathways
  • Further Characterization of CDC25 Mm , a Mammalian Activator of p21ras
  • MAP Kinase Cascade and the Control of Cell Proliferation
  • Accumulation and Mitogenic Activity of Lysophosphatidylinositol in k-ras-Transformed Thyroid Cells
  • Activities Involved in the Modulation of the G Protein EndogenousADP-Ribosylation in Normal and K-ras-Transformed Thyroid Cells
  • The Regulation of TNF-? Receptors in Human Osteosarcoma Cells
  • The Regulatory Subunit of cAMP-Dependent Protein Kinase as a Target for Cancer Diagnosis and Therapy
  • Type I Isoform of PKA is Involved in the Control of Cell Proliferation and Oncogene Transformation of Human Mammary Epithelial Cells: Therapeutic Implications
  • Modulation of the Cell Response to Hyperthermia by Membrane Perturbating Agents
  • MRS Studies on Experimental Tumours Treated with TNF
  • Tumor Vaccines — Perspectives and Practice
  • Clinical applications
  • Tumor Imaging with Radiolabeled Monoclonal Antibodies and Other Specific Ligands
  • Evaluation of p53 Overexpression in Bladder Cancer
  • Biological Factors and Treatment Decision in Early Breast Cancer
  • New Chemotherapeutic Agents: A Selection of Some of the Most Promising New Drugs
  • Degradation of5-Fluorouracil via the Pyrimidine Degradative Pathway
  • Folinic Acid and 5-Fluorouracil ± Interferon Alfa-2b in the Treatment of Advanced Colorectal Cancer: Preliminary Results of a Randomized Study
  • Chronic Exposure to the Tumor Promoter TPA Mimics Differentiating Effects of Serum in Primary Cultures of Cerebellar Granules
  • Transcriptional Control by Nuclear Receptors
  • Models for new therapeutical strategies
  • Therapeutic Opportunities Involving Cellular Oncogenes
  • Molecular Analysis of Fine Needle Aspiration Cytologic Specimens from Suspicious Thyroid Nodules
  • Tumor-associated Macrophages: Cytokine Regulation and Therapeutic Implications
  • Various Cytokines (IL-2, IL-4, IFN-gamma) Show Different Efficiency in Inducing Tumor Rejection
  • Adoptive Immunotherapy of Melanoma with Interleukin-2 and Lymphocytes
  • GM-CSF Augments the IL-4 Induced Cytotoxic Activity of Human Peripheral Blood Mononuclear Cells in the Presence of the Mouse Monoclonal Antibody 17–1A
  • Autologous Bone Marrow Transplantation with Peripheral Stem Cells In vivo Expanded by Chemotherapy and G-CSF