Neural Mechanisms of Anesthesia

Although anesthetics have been used successfully for over 150 years, their mechanisms of action are little understood, a fact that significantly limits our ability to design new and safer agents. In Neural Mechanisms of Anesthesia, leading investigators critically evaluate the latest information on...

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Bibliographic Details
Other Authors: Antognini, Joseph E. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2003, 2003
Edition:1st ed. 2003
Series:Contemporary Clinical Neuroscience
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • I. Introduction
  • 1 The Development of Concepts of Mechanisms of Anesthesia
  • II. Anesthesia, Consciousness, and Memory
  • 2 Mechanisms of Consciousness with Emphasis on the Cerebral Cortical Component
  • 3 Anesthesia Meets Memory: Tools for Critical Appraisal
  • III. Sleep, Coma, and Anesthesia—Similarities and Differences
  • 4 Sleep and Anesthesia
  • 5 Possible Relationships of Anesthetic Coma and Pathological Disorders of Consciousness
  • IV. Neural Mechanisms
  • 6 Cerebral Cortex—Anesthetic Action on the Electroencephalogram: Cellular and Synaptic Mechanisms and Clinical Monitoring
  • 7 Cerebral Mechanisms of Analgesia and Anesthesia in Humans Elucidated by In Vivo Brain Imaging
  • 8 Thalamus
  • 9 The Hippocampus
  • 10 Anesthetic Effects on the Reticular Formation, Brainstem and Central Nervous System Arousal
  • 11 Anesthesia, the Spinal Cord and Motor Responses to Noxious Stimulation
  • 12 Spinal Cord—Dorsal Horn
  • 13 Spinal Cord: Anesthetic Actions on Motor Neurons
  • 14 Simple Genetic Models for Anesthetic Action
  • 15 Genetic Dissection of Anesthetic Action
  • V. Cellular and Molecular Mechanisms
  • 16 General Anesthetic Effects on GABAA Receptors
  • 17 Nicotinic Acetylcholine Receptors and Anesthetics
  • 18 Actions of General Anesthetic on Voltage-Gated Ion Channels
  • 19 Glutamate Receptors: Physiology and Anesthetic Pharmacology
  • 20 General Anesthetic Effects on Glycine Receptors
  • 21 Presynaptic Actions of General Anesthetics
  • 22 The Meyer-Overton Relationship and Its Exceptions
  • 23 Protein Models
  • 24 The Opioid Receptors
  • 25 Local Anesthetics
  • 26 Neuromuscular Blocking Agents and General Anesthesia
  • VI. Future Research
  • 27 The Future of Anesthetic Mechanisms Research