Xenotransplantation Basic Research and Clinical Applications

Xenotransplantation might well provide a revolutionary way of augmenting the function of diseased tissues or replacing organs. This possibility has been advanced by newly acquired understanding of the biological and immunological obstacles to conducting transplantation between species. In Xenotransp...

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Bibliographic Details
Other Authors: Platt, Jeffrey L. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2002, 2002
Edition:1st ed. 2002
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1 Molecular and Cellular Hurdles to Xenotransplantation
  • 2 Pathological Responses to Xenotransplantation
  • 3 Natural Xenoreactive Antibodies
  • 4 Specificity of Xenoreactive Natural Antibodies
  • 5 Biophysical Properties of Xenoreactive Natural Antibodies
  • 6 The Origin of Xenoreactive Natural Antibodies
  • 7 Synthesis of Carbohydrate Antigens Recognized by Xenoreactive Antibodies
  • 8 The Complement Barrier to Xenotransplantation
  • 9 Defects and Amplification of Costimulation Across the Species
  • 10 Antibody-Dependent Effects on Cellular Immunity
  • 11 Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation
  • 12 Current Applications of Cellular Xenografts