Neurotransmitter Transporters Structure, Function, and Regulation

Integrating the many recent advances from DNA technology, Maarten Reith and his contributors fully update all the material in his highly acclaimed first edition, expanding it to include the important progress made in characterizing the structure, function, regulation, and physiological relevance of...

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Bibliographic Details
Other Authors: Reith, Maarten E. A. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2002, 2002
Edition:2nd ed. 2002
Series:Contemporary Neuroscience
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Description
Summary:Integrating the many recent advances from DNA technology, Maarten Reith and his contributors fully update all the material in his highly acclaimed first edition, expanding it to include the important progress made in characterizing the structure, function, regulation, and physiological relevance of each transporter. The new material includes discussions of gene organization and the relationship of polymorphisms of monoamine transporters with a variety of diseases, transgenic animals carrying altered genes for plasma membrane monoamine transporters, and the regulation of transporters by trafficking in relation to their phosphorylation state. Also addressed are transporter imaging techniques that allow in vivo measurement in men and animals, chimera and site-directed mutagenesis studies, and transporter electrophysiology. Many chapters will be of interest to physicians carrying out imaging and postmortem measurements of neurotransmitter transporters in the human brain, and to physicians who study the relation of gene linkages and polymorphisms to psychiatric and other complex human diseases. Complete and up-to-date, Neurotransmitter Transporters: Structure, Function, and Regulation, Second Edition continues to be the most informative and useful review of this most active field, allowing comparison between the characteristics of various neurotransmitter transporters and their biological roles in such a way that progress for one transporter can help move work on another transporter forward
Physical Description:XII, 518 p online resource
ISBN:9781592591589