Lysosomes

In 1976 I wrote a monograph on lysosomes (Lysosomes: A Survey, Springer­ Verlag, Vienna) that was intended as an up-to-date, comprehensive survey. Whatever success I may have achieved then in fulfilling that intention, even the effort now would be foolhardy. The literature has grown so rapidly in th...

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Bibliographic Details
Main Author: Holtzman, Eric
Format: eBook
Language:English
Published: New York, NY Springer US 1989, 1989
Edition:1st ed. 1989
Series:Cellular Organelles
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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505 0 |a 1 Historical Fragments; Methods; Some Terminology -- 2 Endocytosis and Heterophagy -- 3 Acidification; Membrane Properties; Permeability and Transport -- 4 Uses and Abuses of Endocytotic and Heterophagic Pathways -- 5 Autophagy and Related Phenomena -- 6 Extensive Release. Excessive Storage -- 7 Genesis 
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520 |a In 1976 I wrote a monograph on lysosomes (Lysosomes: A Survey, Springer­ Verlag, Vienna) that was intended as an up-to-date, comprehensive survey. Whatever success I may have achieved then in fulfilling that intention, even the effort now would be foolhardy. The literature has grown so rapidly in the past decade that I certainly could not even read all of the essential papers, let alone understand and analyze them. My goal here, therefore, is simply to introduce the major features of lysosomes at a level I hope will be useful both to I;ldvanced students and to researchers interested in obtaining a broad background. This is in keeping with the design of the Cellular Organelles series: the series is more a set of advanced texts than of review monographs. This design carries with it the decision not to support each point by refer­ ences to the original literature. I apologize for the injustice involved in such a decision but feel that in any event it would be impossibly unwieldy to cite, adequately and in a balanced manner, the contributions of the vast network of researchers responsible for the information upon which I draw