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Ubiquitin and the Biology of the Cell

The last several years have been a landmark period in the ubiquitin field. The breadth of ubiquitin's roles in cell biology was first sketched, and the importance of ubiquitin-dependent proteolysis as a regulatory mechanism gained general acceptance. The many strands of work that led to this ne...

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Bibliographic Details
Other Authors: Peters, Jan-Michael (Editor), Harris, J. Robin (Editor), Finley, Daniel (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1998, 1998
Edition:1st ed. 1998
Subjects:
Biochemistry, General
Animal Anatomy / Morphology / Histology
Biochemistry
Animal Anatomy
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • The Ubiquitin System
  • Polyubiquitin Chains
  • The Ubiquitin-Conjugation System
  • The Deubiquitinating Enzymes
  • The 20 S Proteasome
  • The 26 S Proteasome
  • Function of the Proteasome in Antigen Presentation
  • The N-End Rule Pathway
  • Ubiquitin-Dependent Degradation of Transcription Regulators
  • Role of the Ubiquitin—Proteasome Pathway in NF-?B Activation
  • Ubiquitination of the p53 Tumor Suppressor
  • Cell Cycle Control by Ubiquitin-Dependent Proteolysis
  • Ubiquitination of Integral Membrane Proteins and Proteins in the Secretory Pathway
  • Degradation of Ornithine Decarboxylase
  • Ubiquitin and the Molecular Pathology of Human Disease

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