Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis

This volume records the proceedings of the Workshop on Advanced Meth­ ods of Pharmacokinetic and Pharmacodynamic Systems Analysis, organized by the Biomedical Simulations Resource in May 1990. The meeting brought together over 120 investigators from a number of disciplines, including clinical pharma...

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Bibliographic Details
Other Authors: D'Argenio, David (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1991, 1991
Edition:1st ed. 1991
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Pharmacokinetics: Physiological and Biochemical Basis
  • Predicting Oral Drug Absorption in Humans: A Macroscopic Mass Balance Approach for Passive and Carrier-Mediated Compounds
  • Pharmacokinetics of Linear Reversible Metabolic Systems
  • Pharmacokinetic Models for Anticancer and Antiviral Drugs following Administration as Novel Drug Delivery Systems
  • The Significance of Marked “Universal” Dependence of Drug Concentration on Blood Sampling Site in Pharmacokinetics and Pharmacodynamics
  • Pharmacodynamics: Measurements and Models
  • Physiological Alternatives to the Effect Compartment Model
  • Pharmacokinetics/Dynamics of Corticosteroids
  • Variability in Human Cardiovascular Pharmacodynamics
  • Pharmacodynamic Modeling of Thiopental Depth of Anesthesia
  • Pharmacometrics: Modeling, Estimation and Control
  • Residence Time Distributions in Pharmacokinetics: Behavioral and Structural Models
  • Pharmacokinetic Parameter Estimation with Stochastic Dynamic Models
  • Relationships between Intra- or Interindividual Variability and Biological Covariates: Application to Zidovudine Pharmacokinetics
  • On the Single-Point, Single-Dose Problem
  • Application of Stochastic Control Theory to Optimal Design of Dosage Regimens
  • Pharmacotherapeutics: Measurement, Control and Delivery
  • Development of a Fiber Optic Sensor for Detection of General Anesthetics and Other Small Organic Molecules
  • A Bayesian Kinetic Control Strategy for Cyclosporin in Renal Transplantation
  • Targeted Systemic Exposure for Pediatric Cancer Therapy
  • Targeting the Effect Site With a Computer Controlled Infusion Pump
  • Contributors
  • Participants