Excitotoxins Proceedings of an International Symposium held at The Wenner-Gren Center, Stockholm, August 26–27, 1982

Bibliographic Details
Other Authors: Fuxe, Kjell (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1983, 1983
Edition:1st ed. 1983
Series:Wenner-Gren Center International Symposium Series
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Session I Excitotoxic Amino Acids: Localization, Chemistry, Physiology, Pharmacology and Biochemistry
  • Identification of excitatory amino acid pathways in the mammalian nervous system
  • Electrophysiological actions of kainate and other excitatory amino acids, and the structure of their receptors
  • Two types of excitatory amino acid responses in the cat caudate nucleus
  • Recent advances in the pharmacology of excitatory amino acids in the mammalian central nervous system
  • Alteration by kainate of energy stores and neuronal-glial metabolism of glutamate in vitro
  • Receptors for excitotoxins
  • Overview Lecture
  • Excitotoxins: An overview
  • Session II Mechanisms of Excitotoxicity
  • Neuronal degeneration after intracerebral injections of excitotoxins. A histological analysis of kainic acid, ibotenic acid and quinolinic acid lesions in the rat
  • Kainic acid: Insight into its receptor-mediated neurotoxic mechanisms
  • The neurodegenerative properties of intracerebral quinolinic acid and its structural analog cis-2,3- piperidine dicarboxylic acid
  • Studies on excitatory amino acid receptors and their interactions and regulation of pre- and postsynaptic dopaminergic mechanism in the rat telencephalon
  • Electrophysiological and pharmacological studies on kainic acid-induced neuronal activation
  • An analysis of bioelectrical phenomena evoked by microiontophoretically applied excitotoxic amino-acids in the feline spinal cord
  • The role of seizures in kainic acid induced brain damage
  • Excitatory amino acid transmitters in cerebellum and optic tectum
  • Mechanisms of excitotoxins examined in organotypic cultures of rat central nervous system
  • Session III Excitotoxins as Tools in Neuroscience
  • Ibotenate as a tool in neurobiology. Studies on dopaminergic and cholecystokinin immunoreactive neurons after ibotenate induced lesions
  • Characterization of striatal ibotenate lesions and of 6-hydroxydopamine induced nigral lesions by morphometric and densitometric approaches
  • Effects of ibotenate acid stereotactically injected into striatum or hippocampus on local blood flow and glucose utilization in rats
  • Synaptic rearrangements in the kainic acid model of ammon’s horn sclerosis
  • On the problem of distant lesions in behavioural studies utilizing kainic acid
  • Kainic acid injections into the rat neostriatum: Effects on learning and exploration
  • Effects of neurotoxic excitatory amino acids on neuroendocrine regulation
  • Session IV Clinical Aspects
  • Adverse reactions in humans thought to be related to ingestion of elevated levels of free monosodium glutamate (MSG) (Chinese Restaurant Syndrome and Other Reactions)
  • Temporal lobe epilepsy, excitotoxins and the mechanism of selective neuronal loss
  • Huntington’s disease: anti-neurotoxic therapeutic strategies
  • Excitotoxicity in ageing and dementia