Transition States of Biochemical Processes
The transItIOn-state theory has been, from the point of its inception, the most influential principle in the development of our knowledge of reaction mechanisms in solution. It is natural that as the field of biochemical dynamics has achieved new levels of refinement its students have increasingly a...
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| Format: | eBook |
| Language: | English |
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New York, NY
Springer US
1978, 1978
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| Edition: | 1st ed. 1978 |
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| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 1 • Scope and Limitations of the Concept of the Transition State
- 2 • Catalytic Power and Transition-State Stabilization
- 3 • Quantum-Mechanical Approaches to the Study of Enzymic Transition States and Reaction Paths
- 4 • Primary Hydrogen Isotope Effects
- 5 • Secondary Hydrogen Isotope Effects
- 6 • Solvent Hydrogen Isotope Effects
- 7 • Heavy-Atom Isotope Effects in Enzyme-Catalyzed Reactions
- 8 • Magnetic-Resonance Approaches to Transition-State Structure
- 9 • Mapping Reaction Pathways from Crystallographic Data
- 10 • Transition-State Properties in Acyl and Methyl Transfer
- 11 • Transition States for Hydrolysis of Acetals, Ketals, Glycosides, and Glycosylamines
- 12 • Decarboxylations of ?-Keto Acids and Related Compounds
- 13 • The Mechanism of Phosphoryl Transfer
- 14 • Intramolecular Reactions and the Relevance of Models
- 15 • Transition-State Affinity as a Basis for the Design of Enzyme Inhibitors
- 16 • Transition-State Theory and Reaction Mechanism in Drug Action and Drug Design
- Author Index