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140122 ||| eng |
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|a 9781468475449
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| 100 |
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|a Maxwell, George Morrison
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| 245 |
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|a Principles of Paediatric Pharmacology
|h Elektronische Ressource
|c by George Morrison Maxwell
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| 250 |
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|a 1st ed. 1984
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| 260 |
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|a New York, NY
|b Springer US
|c 1984, 1984
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| 300 |
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|a VIII, 408 p
|b online resource
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|a Drugs Which Cause Skin Disease -- 15. The Pharmacology of the Eye -- Structure and Function -- Drug Treatments -- Mydriatics -- Drug Treatment of Glaucoma -- Drug Effects Upon Ocular Function -- 16. General and Specific Chemotherapy -- Antimicrobial Agents -- Drugs Used to Treat Protozoal Infection and Infestation by Multicellular Organisms -- Chemotherapy of Neoplastic Disorders -- 17. Immunity and its Modification by Drugs -- Normal Mechanisms of Immunity -- Active Immunisation -- Passive Immunisation -- Adjuvants of the Immune Response -- Immunosuppressants -- Immune Tolerance -- Hypersensitivity Responses -- Drug Therapy of Hypersensitivity -- Drugs Used in Inflammation -- 18. Ethics and Problems of Clinical Trials in Children -- Some Types of Clinical Trials -- Suggestions for Further Reading
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|a The Psychotropic Agents -- Sedatives and Hypnotics -- Analgesics -- The Anti-convulsant Drugs -- Drugs Affecting the Central Control of Muscle Function -- Anaesthesia -- Clinical Appendix -- 7. The Peripheral Nervous System -- The Autonomic System -- The Physiology of Smooth Muscle -- Drugs Affecting Neuro-muscular Transmission -- 8. The Cardiovascular System -- The Physiology of Cardiac Contraction -- Cardiotonic Drugs -- Cardiotoxic Drugs -- The Physiology of Normal Cardiac Rhythm -- Disturbance of Cardiac Rate and Rhythm -- Drugs Used to Treat Arrhythmias -- Drug Induced Arrthymias -- The Physiology of Blood-pressure Control -- Antihypertensive Drugs -- Drugs Causing Systemic Hypertension -- Pulmonary Hypertension -- Clinical Appendix -- 9. The Alimentary System -- The Physiology of the Mouth, Salivary Glands and Oesophagus -- The Physiology of the Stomach -- The Physiology of the Lower Bowel -- Drugs which Act Upon the Gastrointestinal System -- The Pancreas --
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|a 1. Principles of Drug Action and Disposition -- Chemical Identity of Drugs -- Bonding Mechanisms -- Absorption of Drugs -- Distribution of Drugs -- The Biotransformation of Drugs -- The Excretion of Drugs -- 2. Elementary Pharmacokinetics and Pharmacodynamics -- Pharmacokinetics -- Pharmacodynamics -- 3. The Pharmacology of the Fetus and Placenta -- The Placenta -- The Fetus -- The Effects of Drugs Upon the Fetus -- Fetal Pharmacokinetics -- Teratology -- 4. The Pharmacology of the Perinatal Period -- Intrapartum Phase -- Postpartum Phase -- The Pharmacology of Specific Drugs used in the Newborn -- Drugs and Breast Feeding -- 5. The Pharmacology of the Older Child -- Influence of Physiological Factors on Drug Absorption and Bioavailability -- The Effect of Disease on Drug Absorption and Bioavailability -- Conditions Affecting the Binding, Metabolism and Excretion of Drugs -- Drug Metabolism -- Drug Excretion -- 6. The Central Nervous System -- Anatomy and Organisation --
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|a The Liver and Bile Ducts -- Clinical Appendix -- 10. The Respiratory System -- The Physiology of the Respiratory System -- Drugs Affecting the Respiratory System -- Clinical Appendix -- 11. The Urinary System -- The Physiology of the Kidney -- Drugs Affecting the Kidney -- The Physiology of the Bladder -- Drugs Affecting Bladder Function -- Clinical Appendix -- 12. The Haemopoietic System -- The Physiology of the Red Cell -- Physiology of the Leucocytes -- Haemostasis -- The Fibrinolytic System and Thrombolysis -- 13. The Endocrine System -- The Hypothalamic/Pituitary Complex -- The Pituitary -- The Adrenal Gland -- Inhibitors of Adrenal Steroid Synthesis -- The Thyroid -- The Pancreas -- Androgens and Anabolic Steroids -- Progestogens and Oestrogens -- Agents Affecting Calcium and Phosphorus Metabolism -- Clinical Appendix -- 14. The Pharmacology of the Skin -- Anatomy and Function -- Variations and Diseases -- Treatment with Drugs -- Skin Disinfectants and Antiseptics --
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| 653 |
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|a Humanities and Social Sciences
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| 653 |
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|a Humanities
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| 653 |
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|a Social sciences
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| 653 |
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|a Pharmacology
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| 041 |
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|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 028 |
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|a 10.1007/978-1-4684-7544-9
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| 856 |
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|u https://doi.org/10.1007/978-1-4684-7544-9?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 615
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| 520 |
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|a Pharmacology is fundamental for therapeutics. This is well recognised in the field of internal medicine, for which pharmacological textbooks abound. Paediatric pharmacology however, has largely been viewed as a subsection of general medicine. This is incorrect: it should be seen as a separate and important entity. This book is written from the viewpoint of a paediatrician, but it is addressed to all who have responsibility for the care of children, parti cularly physicians and pharmacists. As the latter may lack familiarity with certain diseases of children, I have added a clinical appendix in certain pertinent areas. My approach in each chapter has been to show the interdependence of physiology and pharmacology. Thus I make no apology for providing a physiological review for most topics. Each chapter is reasonably self-contained. I have presumed that a majority of readers will most often go directly to that section relevant to their immediate requirements, and therefore I have sometimes had to restate important points in more than one place. Nevertheless, for the cover to-cover reader, there will not be an excess of repetition. Since this is not a textbook of adult therapeutics, there will be no discussion of such things as coronary vasodilators. Likewise, the obstetric pharmacology of parturition has been omitted, although I have thoroughly covered the pharmacological problems of the fetus and the infant. I am greatly obliged to generations of my students, both under graduate and postgraduate
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