The Biology of DNA Tumor Viruses With an Introduction by Renato Dulbecco

Milestones in Current Research is a series of reprint collections dis­ tinguished from other such publications by new concepts in preparation, presentation, and intent. The aim of each volume is to gather for a given field the seminal contributions that have defined and shaped the trends within the...

Full description

Bibliographic Details
Other Authors: Schiminovich, Samuel (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1976, 1976
Edition:1st ed. 1976
Series:Milestones in current research
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1. Studies on the Transfer of Subviral Infectivity from SV40-Induced Hamster Tumor Cells to Indicator Cells
  • 2. Activation of Production of Infectious Tumor Virus SV40 in Heterokaryon Cultures
  • 3. Production of SV40 Virus in Heterokaryons of Transformed and Susceptible Cells
  • VI. Transcription of the Viral Genome In Infected and Transformed Cells
  • 1. Virus-Specific RNA in Cells Productively Infected or Transformed by Polyoma Virus
  • 2. Characterization of the Simian Virus 40-specific RNA in Virus-yielding and Transformed Cells
  • 3. Regulation of Transcription of the SV40 DNA in Productively Infected and in Transformed Cells
  • 4. The Transcription of the SV40 Genome in Productively Infected and Transformed Cells
  • 5. Strand Orientation of Simian Virus 40 Transcription in Productively Infected Cells
  • 6. A Map of Simian Virus 40 Transcription Sites Expressed in Productively Infected Cells
  • I. Introduction
  • II. Structure of Viral DNA
  • 1. Evidence for a Ring Structure of Polyoma Virus DNA
  • 2. The Cyclic Helix and Cyclic Coil Forms of Polyoma Viral DNA
  • 3. The Twisted Circular Form of Polyoma Viral DNA
  • 4. A Dye-Buoyant-Density Method for the Detection and Isolation of Closed Circular Duplex DNA: The Closed Circular DNA in HeLa Cells
  • III. Integration State of Viral DNA in Transformed Cells
  • 1. Viral DNA in Polyoma- and SV40-Transformed Cell Lines
  • 2. The Integrated State of Viral DNA in SV40-Transformed Cells
  • IV. Detection of Virus-Specific (T) Antigen
  • 1. A Specific Complement-Fixing Antigen Present in SV40 Tumor and Transformed Cells
  • 2. Detection of Specific Antigen in SV40-Transformed Cells by Immunofluorescence
  • 3. Synthesis of SV40 Tumor Antigen during Replication of Simian Papovavirus (SV40)
  • V. Activation of Infectious Tumor Virus SV40 in Transformed Cells
  • 7. Presence of Cell and Virus Specific Sequences in the Same Molecules of Nuclear RNA from Virus Transformed Cells
  • VII. Temperature-Sensitive Mutant Studies of Cell Transformation in Polyoma Virus
  • 1. Induction of Cellular DNA Synthesis by Polyoma Virus
  • 2. Abortive Transformation by Polyoma Virus
  • 3. Cell-Transforming Ability of a Temperature-Sensitive Mutant of Polyoma Virus
  • 4. Abortive Transformation by the Tsa Mutant of Polyoma Virus
  • 5. Temperature-Dependent Properties of Cells Transformed by a Thermosensitive Mutant of Polyoma Virus
  • VIII. Further Problems in the Biology of Small DNA Viruses
  • 1. Growth Control in Cultured Cells: Selection of Sublines with Increased Sensitivity to Contact Inhibition and Decreased Tumor-Producing Ability
  • 2. Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus
  • Author Index