Pharmacokinetics Mathematical and Statistical Approaches to Metabolism and Distribution of Chemicals and Drugs
Pharmacologists can be considered pioneers of the study of kinetics of materials introduced into biological systems. The study of drug kinetics is particularly suited to a formulation of relatively simple models which make possible an interpretation of the time-dependent nature of various important...
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Format: | eBook |
Language: | English |
Published: |
New York, NY
Springer US
1988, 1988
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Edition: | 1st ed. 1988 |
Series: | NATO Science Series A:, Life Sciences
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Subjects: | |
Online Access: | |
Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- History of Pharmacokinetics
- Conceptual Foundations and Uses of Models in Pharmacokinetics
- Development of Compartmental Concepts
- Modeling of Pharmacokinetic Data
- Mathematical Foundations of Linear Kinetics
- An Introduction to Stochastic Compartmental Models in Pharmacokinetics
- Modeling First-Pass Metabolism
- Saturable Drug Uptake by the Liver: Models, Experiments and Methodology
- Physiological Models, Allometry, Neoteny, Space-Time and Pharmacokinetics
- Equivalence of Bioavai1abi1ity and Efficacy in Drug Testing
- Modeling and Risk Assessment of Carcinogenic Dose-Response
- The Puzzle of Rates of Cellular Uptake of Protein-Bound Ligands
- A Pharmacokinetic Equation Guide for Clinicians
- Pharmacokinetic Studies in Man
- Metabolic Models in Radiation Protection
- Author Index