Sister Chromatid Exchanges 25 Years of Experimental Research Part B Genetic Toxicology and Human Studies

Chromosomes, being well-defined structures that are easily vis­ ible under the optical microscope, readily lend themselves to in­ tense physical and biochemical study. The understanding of the structure and function of this most critical genetic material has progressed through a number of interestin...

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Bibliographic Details
Other Authors: Tice, Raymond (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1984, 1984
Edition:1st ed. 1984
Series:Basic Life Sciences
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Detection of SCE in Rodent Cells Using the Activated Charcoal Bromodeoxyuridine System
  • Assessment of Sister Chromatid Exchange in Spermatogonia and Intestinal Epithelium in Chinese Hamsters
  • Sister Chromatid Exchanges in Mammalian Meiotic Chromosomes
  • Human Studies
  • Removal and Persistence of SCE-Inducing Damage in Human Lymphocytes In Vitro
  • Persistence of SCE-Inducing Lesions after GO Exposure of Human Lymphocytes to Differing Classes of DNA-Damaging Chemicals
  • Proliferative Kinetics and Chemical-Induced Sister Chromatid Exchanges in Human Lymphocyte Cultures
  • Importance of the Mitogen in Sister Chromatid Exchange Studies
  • Serum-and Plasma-Dependent Variations of Benzo(a)pyrene-Induced Sister Chromatid Exchange in Human Lymphocytes
  • Analysis of Sister Chromatid Exchanges in Bloom Syndrome by Use of Endomitotic and Three-Way Differentiation Procedures
  • SCE Induction by Cytostatics and Its Relation to Iatrogenic Leukemogenesis
  • Sister Chromatid Exchange Frequency and Cell Cycle Kinetics in Cancer Patients Treated with Cytostatic Drugs
  • Monitoring Patients on Long-Term Drug Therapy for Genotoxic Effects
  • Practical Applications of the SCE Studies for Guiding and Improving Chemotherapy
  • Genotoxicity of Antiamebic, Anthelmintic, and Antimycotic Drugs in Human Lymphocytes
  • Sister Chromatid Exchange Induction by Cigarette Smoke
  • The SCE Test as a Tool for Cytogenetic Monitoring of Human Exposure to Occupational and Environmental Mutagens
  • Sister Chromatid Exchanges in Workers Exposed to Low Doses of Styrene
  • The Effects of Hypolipidemic Peroxisome Proliferators on the Induction of SCEs
  • Ethylene Oxide and Some Factors Affecting the Mutagen Sensitivity of SCE inHumans
  • General Discussion
  • Complementation Studies in Murine/Human Hybrids Suggest Multiple Etiology for Increased Rate ot Sister Chromatid Exchange in Mammalian Cells
  • Different Properties in Lymphoblastoid Cell Lines from Patients with Bloom Syndrome
  • Study of Basal Cell Nevus Syndrome Fibroblasts after Treatment with DNA-Damaging Agents
  • DNA Interstrand Cross-linking, Repair, and SCE Mechanisms in Human Cells in Special Reference to Fanconi’’s Anemia
  • Human Health Situation and Chromosome Alterations: Sister Chromatid Exchange Frequency in Lymphocytes from Passive Smokers and Patients with Hereditary Diseases
  • Sensitivities of Peripheral Lymphocytes from Healthy Humans and Cancer Patients to Induction of Sister Chromatid Exchanges by Genotoxicants
  • Value and Significance of SCE in Human Leukemia and Cancer
  • SCE and Cell Cycle Studies in Leukemia
  • Sister Chromatid Exchange in Phytohemagglutinin-Stimulated Lymphocytes of Nonfamilial Cutaneous Malignant Melanoma Patients
  • The Relevance of Sister Chromatid Exchange Studies to Public Health: Prevention and Intervention. Introduction to a General Discussion on the Interpretation of Sister Chromatid Exchange Data
  • Summary of General Discussion
  • List of Participants
  • of Part B
  • Sce and Genetic Toxicology
  • Sister Chromatid Exchange Analysis in Cultured Peripheral Blood Leukocytes of the Coldwater Marine Fish, Pacific Staghorn Sculpin (Leptocottus armatus): A Feasible System for Assessing Genotoxic Marine Pollutants
  • SCE Studies in the Chick Embryo and Neonate: Actions of Mutagens in a Developing System
  • SCE Induction by Indirect Mutagens/Carcinogens in Metabolically Active Cultured Mammalian Cell Lines
  • Erythrocyte-Mediated Metabolic Activation Detected by SCE
  • The Effect of Erythrocytes and Hemoglobin on Sister Chromatid Exchange Induction in Cultured Human Lymphocytes Exposed to Aniline HC1
  • Development of Rodent Peripheral Blood Lymphocyte Culture Systems to Detect Cytogenetic Damage In Vivo
  • Accumulation of SCEs in Lymphocytes During Chronic Ingestion of a Mutagen
  • Elimination of Cyclophosphamide-Induced SCE in Lymphocytes of Rats with Time Post-treatment