Regulation and Genetics Genetics of Animal Viruses

The time seems ripe for a critical compendum of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at which relatively few new-truly new-viruses will be di...

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Bibliographic Details
Other Authors: Fraenkel-Conrat, H. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1977, 1977
Edition:1st ed. 1977
Series:Comprehensive Virology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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245 0 0 |a Regulation and Genetics  |h Elektronische Ressource  |b Genetics of Animal Viruses  |c edited by H. Fraenkel-Conrat 
250 |a 1st ed. 1977 
260 |a New York, NY  |b Springer US  |c 1977, 1977 
300 |a XX, 614 p. 33 illus  |b online resource 
505 0 |a 1 Genetics of Polyoma Virus and Simian Virus 40 -- 1. Introduction -- 2. Restriction Enzyme Maps of the Polyoma and SV40 Genomes -- 3. The Lytic Growth Cycle -- 4. Mutants of Polyoma and SV40 -- 5. Viral Functions and the Early Region of the Genome -- 6. Temperature-Dependent Properties of Transformed Cells -- 7. References -- 2 Genetics of Adenoviruses -- 1. Introduction -- 2. Adenovirus Mutants -- 3. Characteristics of the Adenovirus Genetic System -- 4. Phenotypes of Adenovirus Mutants -- 5. Functional Studies Using Adenovirus Mutants -- 6. Critique and Perspectives -- 7. Note Added in Proof -- 8. References -- 3 Genetics of Herpesviruses -- 1. Introduction -- 2. Virus Mutants -- 3. Characterization of Mutants -- 4. Recombination -- 5. Effective Genomes -- 6. Validity of Recombination Analysis -- 7. The Genes of HSV -- 8. Mixed-Morphology Plaques -- 9. Transformation -- 10. Latency -- 11. References -- 4 Genetics of Picornaviruses -- 1. Introduction --  
505 0 |a 2. Definition of a Picornavirus -- 3. The Schizon -- 4. Classification of Picornaviruses -- 5. Genetic Methods -- 6. Interactions of Picornavirus Genomes -- 7. The Genetic Recombination Map of Picornaviruses -- 8. Relation of Genetic Map to Gene Functions -- 9. Relation of Genetic Map to Gene Products -- 10. Sites of Action of Viral Growth Inhibitors -- 11. The Strategy of the Picornavirus Genome -- 12. Conclusions -- 13. References -- 5 Genetics of Togaviruses -- 1. Review of the Structure and Replication of Group A Togaviruses -- 2. Types of Mutants -- 3. Interactions of Togavirus Mutants in Mixed Infections -- 4. Physiological Defects in Temperature-Sensitive Mutants -- 5. References -- 6 Genetics of Rhabdoviruses -- 1. Introduction: Some Relevant Biological Features of Rhabdoviruses -- 2. Coding Capacity of the Genome of Rhabdoviruses -- 3. Rhabdovirus Mutants -- 4.Absence of Recombination -- 5. Complementation --  
505 0 |a 4. Origins of Mutants and Variants -- 5. Types of Mutants and Variants -- 6. Genetic and Paragenetic Phenomena -- 7. Temperature-Sensitive Mutants -- 8. Persistent Infection -- 9. Other Directions -- 10. References -- 10 Genetics of Orthomyxoviruses -- 1. Introduction -- 2. Molecular Biology of the Genome -- 3. Virus Population -- 4. Temperature-Sensitive Mutants -- 5. Conclusion -- 6. References 
505 0 |a 6. Temperature-Sensitive Mutants in the Analysis of Genome Function -- 7. Defectiveness -- 8. Phenotypic Mixing and Pseudotypes -- 9. Host-Controlled Modification -- 10. Virulence and Persistent Infection -- 11. Sigma Virus and Germinal Transmission -- 12. Future Prospects -- 13. References -- 7 Genetics of Reoviruses -- 1. Introduction: Structure and Replication of Reoviruses as They Relate to Genetics -- 2. Genetic Interactions -- 3. Gene Function -- 4. Effect on Host -- 5. References -- 8 Genetics of RNA Tumor Viruses -- 1. Introduction 341 1.1. Scope of This Chapter -- 2. Basic Properties of the Virus Genome -- 3. Nonconditional Mutants and Markers -- 4. Interactions between RNA Tumor Viruses -- 5. Conditional Mutants -- 6. Biochemical Approaches to RNA Tumor Virus Genetics -- 7. Concluding Speculations -- 8. References -- 9 Genetics and Paragenetic Phenomena of Paramyxoviruses -- 1. Introduction -- 2. Properties Relevant to Genetic Analyses -- 3. Virus Populations --  
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653 |a Medical microbiology 
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082 0 |a 616.9041 
520 |a The time seems ripe for a critical compendum of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua­ ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts