Lithium Its Role in Psychiatric Research and Treatment

Psychopharmacology has certainly had the greatest impact on psy­ chiatric theory and practice since the psychoanalytic discoveries by Freud. Beginning more than 20 years ago, psychopharmacology has become a vigorous interdisciplinary science, and over the last 10 to 15 years has witnessed a tremendo...

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Bibliographic Details
Other Authors: Gershon, Samuel (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1973, 1973
Edition:1st ed. 1973
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • VI. Effects on Normals, Productive Cyclothymics, and the Creative Personality
  • VII. Prophylaxis
  • VIII. Lithium versus Electroshock Therapy
  • IX. Summary
  • X. References
  • 1 A Narrative Account of Lithium Usage in Psychiatry
  • I. Discovery
  • II. Uses of Lithium
  • III. Commercial Production of Lithium
  • IV. Conclusion
  • V. References
  • 2 The Chemistry and Biochemistry of Lithium
  • I. Introduction
  • II. General Properties of Cations
  • III. Chemistry of Lithium
  • IV. The Biochemistry of Lithium
  • V. Concluding Remarks
  • VI. References
  • 3 Pharmacology—Lithium Absorption, Distribution, Renal Handling, and Effect on Body Electrolytes
  • I. Absorption
  • II. Distribution
  • III. Renal Handling
  • IV. Effect on Body Electrolytes
  • V. Summary
  • VI. References
  • 4 Pharmacology—The Effects of Lithium on Biogenic Amines
  • I. Introduction
  • II. Catecholamines
  • III. Indoleamines
  • IV. Conclusion
  • V. Acknowledgments
  • VI. References
  • 5 Pharmacology—Lithium’s Effects on Cyclic AMP, Membrane Transport, and Cholinergic Mechanisms
  • I. Cyclic AMP
  • II. Membrane Transport
  • III. Cholinergic Mechanisms
  • IV. Acknowledgment
  • VI. References
  • 10 Preparations, Dosage, and Control
  • I. Preparations
  • II. Initial Treatment of Mania: Dosage and Control
  • III. Maintenance Treatment
  • IV. References
  • 11 The Affective Disorders: Clinical and Epidemiological Aspects
  • I. Introduction
  • II. The Classification Problem
  • III. Epidemiology
  • IV. Clinical Depressions
  • V. Mania and Elations
  • VI. Conclusions
  • VII. Acknowledgment
  • VIII. References
  • 12 Lithium in Mania: Clinical Trials and Controlled Studies
  • I. Introduction
  • II. Uncontrolled and Single-Blind Studies
  • III. Controlled Studies
  • IV. Experimental Drugs in the Treatment of Mania
  • V. Summary and Conclusions
  • VI. References
  • 13 Lithium and Depression
  • I. Introduction
  • II. Uncontrolled Studies
  • III. Controlled Studies
  • IV. Discussion
  • V. Summary
  • VI. Acknowledgment
  • VII. References
  • 14 Prophylactic Lithium Maintenance Treatment in Recurrent Endogenous Affective Disorders
  • I. Introduction
  • II. Terminology
  • III. Lithium Maintenance Treatment
  • IV. Remarks
  • V. Acknowledgments
  • VI. References
  • 15 Lithium in Other Psychiatric Disorders
  • I. Introduction
  • II. The Use of Lithium in Schizophrenia
  • III. The Use of Lithium in Neuroses and Personality Disorders without an Affective Component
  • IV. The Use of Lithium in Neuroses and Personality Disorders with an Aggressive or Affective Component
  • V. The Use of Lithium in Epilepsy
  • VI. The Use of Lithium in Childhood Disorders
  • VII. The Use of Lithium for Premenstrual Tension
  • VIII. The Use of Lithium in Normals
  • IX. Summary and Discussion
  • X. References
  • 16 Overview of Therapeutic and Prophylactic Trials with Lithium in Psychiatric Patients
  • I. Introductory Analysis
  • II. Confusion in Classification of the Affective Disorders: A Proposed Model for Biogenetic Investigations
  • III. Therapeutic Effects in Mania
  • IV. Effects in Depression
  • V. Effects in Other Psychiatric Disorders
  • V. References
  • 6 Pharmacology—Neurophysiology of Lithium
  • I. Introduction
  • II. Microelectrode Studies
  • III. Animal Studies
  • IV. Human Studies
  • V. Summary and Conclusions
  • VI. References
  • 7 Pharmacology—Toxicology of the Lithium Ion
  • I. Introduction
  • II. Mild-Moderate Toxic Side Effects: Minor Lithium Intolerance
  • III. Lithium Poisoning
  • IV. General Considerations
  • V. Complications of Lithium Treatment
  • VI. Other Effects of Lithium Treatment
  • VII. References
  • 8 Pharmacology—Lithium Teratology
  • I. Introduction
  • II. General Principles
  • III. Studies in Premammalian Species
  • IV. Studies in Mammals Other than Man
  • V. Chromosome Studies
  • VI. Human Studies
  • VII. The Use of Lithium in Pregnancy
  • VIII. Acknowledgment
  • IX. References
  • 9 Pharmacology—The Biology of Lithium
  • I. Introduction
  • II. LithiumTreatment and Electrolyte Balance
  • III. Lithium Metabolism
  • IV. Central Effect of Lithium
  • V. Acknowledgment