Hybridomas and Cellular Immortality

The ability to "immortalize" immunologically-useful cells by hybridization with a unique cancer cell has revolutionized serological studies and has revealed new potential applications in all fields of biological sciences. This volume presents the studies from a highly successful national s...

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Bibliographic Details
Other Authors: Tom, Baldwin H. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1983, 1983
Edition:1st ed. 1983
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 2. Production of Human Immunoglobulin Secreting Clones Without the Use of H.A.T. Sensitive Fusion Partners
  • 3. Species Distribution of Antigenic Sites on Mouse LDH-C4 Determined by Monoclonal Antibodies
  • 4. A New Non-Immunoglobulin Producing Human Myeloma Cell line for Production of Hybridomas
  • 5. Monoclonal Antibodies to Human Prostate and Bladder Tumor Associated Antigens
  • 6. Antibody Purification by Recycling Isoelectric Focusing
  • 7. Monoclonal Antibodies Against Human Ejaculated Sperm-Application in Antibody Mediated Infertility
  • 8. Analysis of Peripheral Blood and Salivary Gland Lymphocytes in Sjogren’s Syndrome
  • 9. A Monoclonal Antibody Which Identifies a Subpopulation of Human B Lymphocytes and Monocytes
  • 10. In Vivo Localization of Tumor Associated Antigens with Radioactively Labeled Monoclonal Antibodies
  • 11. Characteristics of Monoclonal Antibodies to Herpes Simplex Type 2
  • 20. Isolation of Antibodies that are Specific for Human Carboxypeptidase B But Not for the Zymogen Procarboxypeptidase B by Affinity Chromatography
  • 21. Dexamethasone Effects on Hybridoma Formation
  • 22. Class Antigen in the Rat: Evidence for More Than One Using Monoclonal Antibodies
  • 23. An Immunohistochemical Method for Large Scale Specificity Screening of Monoclonal Antibodies
  • 24. Monoclonal Antibodies to Chicken Hemopoietic-Lymphoid Cellular Differentiation Antigens
  • Author Index
  • I. Introduction To Hybridomas
  • 1 Somatic Cell Hybrids and Hybridomas
  • II. Antibody Diversity And Lymphocyte Differentiation
  • 2 The Nature and Origin of Antibody Diversity
  • 3 Hematopoietic Tumors: Normal or Abnormal Models of Leukocyte Differentiation?
  • 4 Dissection of Human Immunoregulatory T Lymphocytes: Implications for Understanding Clinical Disease
  • 5 Immune (?) Interferon and Lymphotoxin Production by T Cell Lines and Hybrids
  • III. Monoclonal Antibodies as Probes of Antigen Structure
  • 6 Partial Structural Characterization of Human HLA-DR Subsets Using Monoclonal Antibodies
  • 7 Monoclonal Antibodies for Analysis of HLA Antigens: Further Studies with the W6/32 Antibody
  • IV. Monoclonal Antibodies in Diagnosis and Therapy
  • 8 Monoclonal Antibodies to Hepatitis B Surface Antigen
  • 9 Wandering Around the Cell Surface: Monoclonal Antibodies Against Human Neuroblastoma and Leukemia Cell Surface Antigens
  • 10 Monoclonal Antibodies to Human Melanoma-Associated Antigen p97
  • 11 A Biochemical and Biosynthetic Analysis of Human Melanoma-Associated Antigens with Monoclonal Antibodies
  • 12 Monoclonal Antibodies to a Tumor Specific Antigen on Rat Mammary Carcinoma Sp4 and their use in Drug Delivery Systems
  • 13 Monoclonal Antibody to a Tumor Specific Epitope of Murine Lymphoma Cells: Use in Characterization of Antigen and in Immunotherapy
  • V. New and Relevant Methodology
  • 14 Human Hybridomas
  • 15 Procedures for In Vitro Immunization and Monoclonal Antibody Production
  • 16 Liposome-facilitated In Vitro Induction of Primary Cell-Mediated Immunity to Human Cancer Antigens: Potential Adjunct to Hybridoma Technology
  • 17 Comparison of Three Immunoassays for Screening Anti-Hepatitis B Hybridomas
  • VI. Poster Abstracts
  • 1. T-Lymptocyte Subsets of Rhesus Macaque as Determinedby Monoclonal Antibodies: T?, T?, T-NULL, and Histamine Receptor Bearing T Lymphocytes
  • 12. Type Specific Monoclonal Antibodies to Equine Infectious Anemia Virus: Development and Use in the Characterization of Canine and Feline Derived Viruses
  • 13. Biochemical and Biological Analysis of Venezuelan Equine Encephalomyelitis Viruses (VEE) Using Monoclonal Antibodies
  • 14. Monoclonal Antibodies Specific for Herpes Simplex Virus Type 1 Mediate Antiviral Effects In Vitro and In Vivo
  • 15. Monoclonal Antibodies Against Antigens of Amastigotes and Epimastigotes of Trypanosma Cruzi
  • 16. Differential Effects of Four Monoclonal Antibodies to Human ?2-Microglobulin on In Vitro Lymphocyte Functions
  • 17. Selective Inhibition of Functional Sites on Cell Bound Human C3b By Monoclonal Antibodies
  • 18. Generation of Monoclonal Antibodies Reacting With Human Normal and Neoplastic MammaryDuct Epithelial Cells
  • 19. Resolution of Human Liver Mao A and B Using A Monoclonal Antibody Immunoaffinity Column