Advanced Organic Chemistry Part B: Reactions and Synthesis
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer US
1977, 1977
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| Edition: | 1st ed. 1977 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- of Part B
- 1. Alkylation of Carbon via Enolates and Enamines
- 1.1. Generation of Carbon Nucleophiles by Proton Abstraction
- 1.2. Kinetic Versus Thermodynamic Control in Formation of Enolates
- 1.3. Other Means of Generating Enolates
- 1.4. Alkylations of Enolates
- 1.5. Generation and Alkylation of Dianions
- 1.6. Solvent Effects in Enolate Alkylations
- 1.7. Oxygen Versus Carbon as the Site of Alkylation
- 1.8. Alkylations of Aldehydes, Esters, Nitriles, and Nitro Compounds
- 1.9. The Nitrogen Analogs of Enols and Enolates—Enamine Alkylations
- 1.10. Alkylation of Carbon by Conjugate Addition
- General References
- Problems
- 2. Reactions of Nucleophilic Carbon Species with Carbonyl Groups
- 2.1. Aldol Condensation
- 2.2. Related Condensation Reactions
- 2.3. The Mannich Reaction
- 2.4. Acylation of Nucleophilic Carbon
- 2.5. The Wittig Reaction
- 2.6. Sulfur Ylides as Nucleophiles
- 2.7. Nucleophilic Addition-Cyclization
- General References
- Problems
- 3. Addition Reactions of Carbon-Carbon Multiple Bonds
- 3.1. Addition of Hydrogen
- 3.2. Addition of Hydrogen Halides
- 3.3. Hydration and Other Acid-Catalyzed Additions
- 3.4. Oxymercuration
- 3.5. Addition of Halogens to Olefins
- 3.6. Addition of Other Electrophilic Reagents
- 3.7. Electrophilic Substitution Alpha to Carbonyl Groups
- 3.8. Hydroboration
- 3.9. Additions to Allenes and Alkynes
- General References
- Problems
- 4. Reduction of Carbonyl and Other Functional Groups
- 4.1. Hydride-Transfer Reagents
- 4.2. Hydrogen-Atom Donors
- 4.3. Dissolving-Metal Reductions
- General References
- Problems
- 5. Organometallic Compounds
- 5.1. Organic Derivatives of Group I and II Metals
- 5.2. Organic Derivatives of Group IIb Metals
- 5.3. Organic Derivatives of Transition Metals
- 5.4. Catalysis ofRearrangements by Metal Ions and Complexes
- 5.5. Organometallic Compounds with ?-Bonding
- General References
- Problems
- 9.3. Cleavage of Carbon-Carbon Double Bonds
- 9.4. Selective Oxidative Cleavages at Other Functional Groups
- 9.5. Oxidations of Ketones and Aldehydes
- 9.6. Allylic Oxidation of Olefins
- 9.7. Oxidations at Unfunctionalized Carbon Atoms
- General References
- Problems
- 10. Multistep Syntheses
- 10.1. Protective Groups
- 10.2. Synthetic Equivalent Groups
- 10.3. Asymmetric Syntheses
- 10.4. Synthetic Strategy
- General References
- Problems
- 11. Synthesis of Macromolecules
- 11.1. Polymerization
- 11.2. Peptide and Protein Synthesis
- 11.3. Nucleosides, Nucleotides, and Polynucleotides
- General References
- Problems
- References for Problems
- 6. Cycloadditions and Unimolecular Rearrangements and Eliminations
- 6.1. Cycloaddition Reactions
- 6.2. Photochemical Cycloadditions
- 6.3. SigmatropicRearrangements
- 6.4. Unimolecular Thermal Elimination Reactions
- General References
- Problems
- 7. Aromatic Substitution Reactions
- 7.1. Electrophilic Aromatic Substitution
- 7.2. Nucleophilic Aromatic Substitution
- 7.3. Substitutions Involving Aryl Free Radicals
- 7.4. Reactivity of Polycyclic Aromatics
- General References
- Problems
- 8. Reactions Involving Carbenes, Nitrenes, and Other Electron-Deficient Intermediates
- 8.1. Carbenes
- 8.2. Nitrenes
- 8.3. Rearrangements of Electron-Deficient Intermediates
- 8.4. Fragmentation Reactions
- 8.5. Some Synthetically Useful Carbonium-Ion Reactions
- General References
- Problems
- 9. Oxidations
- 9.1. Oxidation of Alcohols to Aldehydes, Ketones, or Carboxylic Acids
- 9.2. Addition of Oxygen at Carbon-Carbon Double Bonds