Advances in Human Genetics 15
| Other Authors: | |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer US
1986, 1986
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| Edition: | 1st ed. 1986 |
| Series: | Advances in Human Genetics
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 1 Chromosomal Abnormalities in Leukemia and Lymphoma: Clinical and Biological Significance
- Methods
- Chronic Myelogenous Leukemia (CML)
- Acute Nonlymphocytic Leukemia (ANLL) de Novo
- Acute Nonlymphocytic Leukemia Induced by Treatment
- Acute Lymphocytic Leukemia (ALL)
- Malignant Lymphoma (ML)
- The Biological Significance of Consistent Chromosomal Abnormalities
- References
- 2 An Algorithm for Comparing Two-Dimensional Electrophoretic Gels, with Particular Reference to the Study of Mutation
- The Theory and Practice of Two-Dimensional Gels, with Particular Reference to the Study of Mutation
- The General Problem of Image Comparison
- A Set of Algorithms for Detecting Potential Mutational Events
- Validation of the Current Algorithm
- Improving the System: Necessary Developments in the Algorithm
- Improving the System: Necessary Developments in Two-Dimensional Gels
- Experimental Validation of This Approach
- Some Issues in Data Management
- Summary
- Recent Developments
- References
- 3 The Human Argininosuccinate Synthetase Locus and Citrullinemia
- Historical Aspects
- Biology of the Argininosuccinate Synthetase Locus
- Biochemistry of the Enzyme
- Cloning of Human Argininosuccinate Synthetase Gene
- Argininosuccinate Synthetase Pseudogenes
- Citrullinemia—Clinical Aspects
- Molecular Analysis in Citrullinemia
- Molecular and Genetic Analysis of Regulation
- Gene Transfer Using the Argininosuccinate Synthetase Locus
- Future Directions
- References
- 4 Molecular Genetics of the Human Major Histocompatibility Complex
- Characterization of the HLA Genes
- HLA Genes As Probes
- Conclusion
- References
- 5 Genetics of Human Alcohol and Aldehyde Dehydrogenases
- Alcohol Dehydrogenases
- Aldehyde Dehydrogenases
- References
- Addendum