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140122 ||| eng |
| 020 |
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|a 9781461538325
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| 100 |
1 |
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|a Giraldi, Tullio
|e [editor]
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| 245 |
0 |
0 |
|a Triazenes
|h Elektronische Ressource
|b Chemical, Biological, and Clinical Aspects
|c edited by Tullio Giraldi, Thomas Connors, Giuseppe Cartei
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| 250 |
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|a 1st ed. 1990
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| 260 |
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|a New York, NY
|b Springer US
|c 1990, 1990
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| 300 |
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|a VIII, 227 p
|b online resource
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| 505 |
0 |
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|a Triazenes: Synthesis and Chemical Properties -- Mechanisms of the Biological Actions of Triazenes -- Triazenes and Triazene N-Oxides: Antitumour Action in Animal Tumour Systems -- Antimestastatic Action of Triazene Derivatives -- Effects of Triazenes on Immune Responses -- Xenogenization of Experimental Tumors by Triazene Derivatives -- The Metabolism of Antineoplastic Triazenes -- Notes on the Metabolism, Pharmacokinetics and Mode of Action of N-Methyl and N-Ethyl-Triazenes in Relation to Their Pharmacological Activity -- Clinical Use of Triazenes -- Clinical Studies with the p-Carboxyl-Dimethyl-Phenyl-Triazene CB10–277 -- Triazenes: Therapeutic Considerations and Perspectives -- Antitumor Imidazotetrazines: Prodrugs Targeted to the Major Groove of DNA -- O6-Alkylguanine-DNA-Alkyltransferase Gene Expression and the Cytotoxicity of Triazenes -- N-Methylmelamines, a Unique Class of Anti-Tumour Agents? -- Experimental Background and Early Clinical Studies with Imidazotetrazine Derivatives -- ‘O6-Alkylguanine-DNA-Alkyltransferase: Significance, Methods of Measurement and Some Human Tumor and Normal Tissue Levels’ (Contributions of the Workshop) -- Summary of Poster-Sessions -- Contributors
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| 653 |
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|a Cancer
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| 653 |
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|a Biochemistry
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| 653 |
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|a Cancer Biology
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| 653 |
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|a Oncology
|
| 700 |
1 |
|
|a Connors, Thomas
|e [editor]
|
| 700 |
1 |
|
|a Cartei, Giuseppe
|e [editor]
|
| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
| 989 |
|
|
|b SBA
|a Springer Book Archives -2004
|
| 028 |
5 |
0 |
|a 10.1007/978-1-4615-3832-5
|
| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-1-4615-3832-5?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 616.994
|