Emerging Targets in Antibacterial and Antifungal Chemotherapy
Emerging Targets in Antibacterial and Antifungal Chemotherapy offers constructive ideas to researchers that could lead to the discovery of entirely new classes of drugs. The authors emphasize new topics rather than review work on known antibacterials and antifungals, and identify new targets--either...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer US
1992, 1992
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| Edition: | 1st ed. 1992 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Antibacterial Chemotherapy
- 1. Historical Perspectives of Approaches to Antibiotics Discovery
- 2. Bacterial Pathogens for the 1990s: A Case for New Drug Development
- 3. DNA Replication
- 4. RNA Synthesis in Bacteria: Mechanism and Regulation of Discrete Biochemical Events at Initiation and Termination
- 5. Bacterial Cell Division
- 6. Fatty Acid Biosynthesis
- 7. Protein Secretion in Bacteria: A Chemotherapeutic Target?
- 8. Cytosolic Enzymes in Peptidoglycan Biosynthesis as Potential Antibacterial Targets
- 9. Strategies in ?-lactam Design
- 10. Lipid A Biosynthesis
- 11. Compromising the Protective Barrier of the Gram-Negative Bacterial Cell Surface
- 12. Bacterial Virulence Factors as Targets for Chemotherapy
- Antifungal Chemotherapy
- 13. Invasive Fungal Infections: Problems and Challenges for Developing New Antifungal Compounds
- 14. Topoisomerase II Inhibitors: Prospects for New Antifungal Agents
- 15. Functions for Sterols in Yeast Membranes
- 16. Biochemical Aspects of Ergosterol Biosynthesis Inhibition
- 17. Rationally Designed Inhibitors of Sterol Biosynthesis
- 18. Chitin Synthase as a Chemotherapeutic Target
- 19. Glucan Biosynthesis in Fungi and its Inhibition
- 20. Virulence-Associated Mannoproteins in Candida Albicans
- 21. Screening for Antifungal Activity
- 22. Chemotherapeutic Targets in Pneumocystis Carinii