The Immunoglobulin a System

The International Symposium on the Immunoglobulin A System was organized in observance of the twenty-fifth anni­ versary of the School of Dentistry of the University of Ala­ bama in Birmingham. Immunoglobulin A was chosen as the sub­ ject of the Symposium because of its broad scope in relation to al...

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Bibliographic Details
Other Authors: Mestecky, Jiri (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1974, 1974
Edition:1st ed. 1974
Series:NATO Science Series B:, Physics
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Physical-Chemical Characteristics of J Chains Obtained from IgM
  • DISCUSSION II
  • Session C Structure Chairman: Jiri Mestecky
  • Isolation, Properties, and Structure of Human IgA Myeloma Globulins
  • Amino Acid Sequence Studies of Human IgA Myeloma Proteins
  • Structural Studies on a Human IgA1 Myeloma Protein with a Carboxy Terminal Deletion
  • The Hinge Peptide of an IgA2m(2) Myeloma Protein
  • The Carbohydrate Composition of Glycopeptides Isolated from IgA2 Immunoglobulin
  • Mouse IgA Myeloma Proteins with Alpha Chain Deletions: A Comparison with Human Alpha Chains with Deletions
  • DISCUSSION I
  • Evidence for a Common Synthetic Origin for Secretory and Serum IgA
  • Studies on the Primary Structure of Human Secretory Component
  • Production of an Fc Fragment from Human Immunoglobulin A by an IgA-Specific Bacterial Protease
  • Precipitin Cross-Reactions between Human and Animal J-Chains
  • Disulfide Bridges of Human Immunoglobulins A1 and A2
  • DISCUSSION II
  • Session A Developmental and Cellular Aspects Chairman: Lars A. Hanson
  • The IgA System in Connection with Local and Systemic Immunity
  • Origin, Distribution, and Differentiation of IgA-Producing Cells
  • Cell Types Contributing to the Biosynthesis of sIgA
  • DISCUSSION I
  • Gut-Associated Lymphoblasts and Intestinal IgA Plasma Cells
  • Bronchial Lymphoid Tissue
  • The Origin of Monomeric and Polymeric Forms of IgA in Man
  • Cytophilic Properties of IgA to Human Neutrophils
  • DISCUSSION II
  • Session B Structure, Biosynthesis, and Genetics Chairman: J. Claude Bennett
  • Characteristics of SC-Ig Complexes Formed in vitro
  • Association of S-IgA Subunits
  • Modulation of the Assembly of Immunoglobulin Subunits
  • DISCUSSION I - E. C. Franklin, Initial Discussant
  • Mechanism of Immunoglobulin Polymer Assembly
  • Assembly and Secretion of Immunoglobulin A
  • Special Characteristics of the IgA2 Subclass
  • Genetics and Evolution of Human Immunoglobulin A
  • Session D Function Chairman: Frederick W. Kraus
  • Implications of Secretory Immune System in Viral Infections
  • The Role of the Secretory Immune System in Protection Against Agents Which Infect the Respiratory Tract
  • The Role of Immunization in Controlling Antigen Uptake from the Small Intestine
  • Lack of C3 Activation through Classical or Alternate Pathways by Human Secretory IgA Anti-Blood Group A Antibody
  • DISCUSSION I
  • Bacterial Adherence to Mucosal Surfaces and Its Inhibition by Secretory Antibodies
  • Specificity of Antibodies to Streptococcus Mutans; Significance in Inhibition of Adherence
  • Secretory Antibodies in Milk of Swine Against Transmissible Gastroenteritis Virus
  • Secretory IgA and Direct Killing of Shigella by Serum Components
  • DISCUSSION II
  • Session E Clinical Considerations Chairman: Max D. Cooper
  • Current Knowledge on Alpha Chain Disease
  • The Cellular Basis of IgA Deficiency in Humans
  • Alpha Chain Determinants on the Membrane of Immunoglobulin Synthesizing Cells
  • Secretory and Serum IgA in Children with Protein-Calorie Malnutrition
  • Studies of Secretory Antibodies to E. Coli in Human Urine Compared to the Serum Antibody Content
  • Secretory IgA: An Adolescent Coming of Age
  • DISCUSSION I
  • Types of Size Heterogeneity of IgA Molecules Isolated from Myeloma and Normal Human Serum
  • Distribution of IgA Subclasses in Sera and Bone Marrow Plasma Cells of 21 Normal Individuals
  • Selective IgA Deficiency and Chronic Obstructive Pulmonary Disease — A Family Study
  • DISCUSSION II
  • Session F The IgA Antibody Response Implications for Oral Health Chairman: Alexander R. Lawton
  • The Induction and Characterization of Secretory IgAAntibodies
  • Human Nasal Exocrine IgA Antibody: Formation and Some Activities
  • The IgA Antibody-Forming Cell Response in the Rabbit Submandibular Gland Following Several Different Methods of Immunization
  • The Establishment of Systemic Immunity Following Antigenic Stimulation of the Lymphoid Tissue of the Gastrointestinal Mucosa
  • DISCUSSION I
  • The Relationship between Serum and Salivary Antibodies and Cell Mediated Immunity in Oral Disease in Man
  • Oral Manifestations of IgA Deficiency
  • DISCUSSION II
  • Conclusion
  • Impressions, Summary, and Questions Raised by the IgA Symposium
  • Program Participants